Gupta Naina, Terrell William, Schoenfield Lynn, Kirsch Claudia, Cebulla Colleen M
Havener Eye Institute, Department of Ophthalmology and Visual Science, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Havener Eye Institute, Department of Ophthalmology and Visual Science, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA; Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Ocul Oncol Pathol. 2016 Apr;2(3):140-3. doi: 10.1159/000441526. Epub 2015 Nov 20.
BACKGROUND/AIMS: To report a case and the unique histopathology of a necrotic uveal melanoma mimicking advanced Coats' disease in a young adult.
A 26-year-old male presented with a blind, painful eye, total exudative retinal detachment, and bulbous aneurysms consistent with Coats' disease. No masses were visualized on ultrasound or CT scan, and the patient underwent enucleation of the eye.
Histopathology of the involved eye confirmed a necrotic uveal melanoma with persistent spindle cells forming a collar around residual tumor vessels.
Careful consideration is needed in approaching any patient with a blind, painful eye and opaque media, even in younger populations.
背景/目的：报告一例年轻成年人坏死性葡萄膜黑色素瘤病例，其具有模仿晚期科茨病的独特组织病理学表现。
一名26岁男性因失明、疼痛眼、完全渗出性视网膜脱离以及与科茨病相符的球囊样动脉瘤前来就诊。超声或CT扫描均未发现肿物，患者接受了眼球摘除术。
患眼的组织病理学检查证实为坏死性葡萄膜黑色素瘤，残留的梭形细胞围绕残留的肿瘤血管形成一个环。
对于任何有失明、疼痛眼和混浊介质的患者，即使是年轻人群，也需要仔细考虑。
