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本文引用的文献

1
Pathogenesis of Nonalcoholic Steatohepatitis.非酒精性脂肪性肝炎的发病机制
Gastroenterology. 2016 Jun;150(8):1769-77. doi: 10.1053/j.gastro.2016.02.066. Epub 2016 Feb 27.
2
Novel Molecular Mechanisms in the Development of Non-Alcoholic Steatohepatitis.非酒精性脂肪性肝炎发生发展中的新型分子机制
Diabetes Metab J. 2016 Feb;40(1):1-11. doi: 10.4093/dmj.2016.40.1.1.
3
Management of NAFLD: a stage-based approach.非酒精性脂肪性肝病的管理：基于分期的方法。
Nat Rev Gastroenterol Hepatol. 2016 Apr;13(4):196-205. doi: 10.1038/nrgastro.2016.3. Epub 2016 Feb 24.
4
Hepatocyte mitochondrial DNA drives nonalcoholic steatohepatitis by activation of TLR9.肝细胞线粒体DNA通过激活TLR9驱动非酒精性脂肪性肝炎。
J Clin Invest. 2016 Mar 1;126(3):859-64. doi: 10.1172/JCI83885. Epub 2016 Jan 25.
5
Lipid-induced hepatocyte-derived extracellular vesicles regulate hepatic stellate cell via microRNAs targeting PPAR-γ.脂质诱导的肝细胞衍生细胞外囊泡通过靶向PPAR-γ的微小RNA调节肝星状细胞。
Cell Mol Gastroenterol Hepatol. 2015 Nov 1;1(6):646-663.e4. doi: 10.1016/j.jcmgh.2015.07.007.
6
Hepatic inflammation and fibrosis: functional links and key pathways.肝脏炎症与纤维化：功能联系及关键通路
Hepatology. 2015 Mar;61(3):1066-79. doi: 10.1002/hep.27332. Epub 2015 Jan 28.
7
Toll-like receptor 7-mediated type I interferon signaling prevents cholestasis- and hepatotoxin-induced liver fibrosis.Toll 样受体 7 介导的 I 型干扰素信号转导可预防胆汁淤积和肝毒素诱导的肝纤维化。
Hepatology. 2014 Jul;60(1):237-49. doi: 10.1002/hep.26981. Epub 2014 May 27.
8
Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease.非酒精性脂肪性肝病中线粒体的适应性改变和功能障碍。
Hepatology. 2013 Oct;58(4):1497-507. doi: 10.1002/hep.26226. Epub 2013 Aug 7.

Hepatocyte mitochondrial DNA released in microparticles and toll-like receptor 9 activation: A link between lipotoxicity and inflammation during nonalcoholic steatohepatitis.

作者信息

Inzaugarat Maria Eugenia, Wree Alexander, Feldstein Ariel E

机构信息

Department of Internal Medicine III, University Hospital, RWTH-Aachen, Aachen, Germany.

Department of Pediatric Gastroenterology, University of California San Diego (UCSD) and Rady Children's Hospital, San Diego, CA.

出版信息

Hepatology. 2016 Aug;64(2):669-71. doi: 10.1002/hep.28666. Epub 2016 Jun 24.

DOI:10.1002/hep.28666
PMID:27239763
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4956555/
Abstract
摘要