Bharti Bhartendu, Syed Kamran Asif, Ebenezer Kala, Varghese Ajoy Mathew, Kurien Mary
Former Registrar, Department of ENT, Christian Medical College, Vellore, India (Presently Assistant Professor, Department of ENT, Himalayan Institute of Medical Sciences, Dehradun, India.
Assistant Professor, Department of ENT, Christian Medical College, Vellore, India.
Int J Pediatr Otorhinolaryngol. 2016 Jun;85:84-90. doi: 10.1016/j.ijporl.2016.03.025. Epub 2016 Mar 28.
To identify acute laryngeal injuries among pediatric patients intubated for more than 48hours, and to correlate these injuries with clinical variables.
Pediatric Intensive Care Unit (PICU) of a tertiary level hospital in India.
Prospective, observational study. Thirty-four children meeting the inclusion and exclusion criteria were recruited into the study after obtaining informed consent from the parents. A bedside, flexible, fiberoptic laryngoscopy was done within the first 24hours of extubation. Laryngeal injuries were documented and graded. Individual types of laryngeal injuries were correlated to the duration of intubation, size of the tube, the experience of the intubator and the patient's demographics. A repeat endoscopy was done in the outpatient department, 3-4 weeks after extubation, and findings noted.
97% had acute laryngeal injury, of which 88% were significant. Erythema was the most common form of injury. Duration of intubation, with a mean of 4.5 days, showed a trend towards significance (p=0.06) for association with subglottic narrowing. Laryngeal injuries were similar with both cuffed and uncuffed tubes. Age of the subject, size of the tube and skill level of the intubator did not correlate with the laryngeal injuries. 18% required intervention for post-extubation laryngeal lesions. Three (10%) children had post-extubation stridor, and of these, two needed surgical intervention (6%).
Post-extubation laryngeal injuries are not uncommon. Fiberoptic endoscopy is an inexpensive and cost-effective tool for bedside evaluation of post-intubation status in pediatric larynx. Early diagnosis of post-intubation laryngeal injuries in children can prevent long term sequelae. Hence, post-extubation fiberoptic laryngoscopy should be done routinely in pediatric population.
确定插管超过48小时的儿科患者中的急性喉损伤,并将这些损伤与临床变量相关联。
印度一家三级医院的儿科重症监护病房(PICU)。
前瞻性观察研究。在获得家长知情同意后,招募了34名符合纳入和排除标准的儿童进入研究。在拔管后的头24小时内进行床边柔性纤维喉镜检查。记录并分级喉损伤情况。将喉损伤的个体类型与插管持续时间、导管尺寸、插管者经验和患者人口统计学特征相关联。在门诊进行拔管后3 - 4周的重复内镜检查,并记录结果。
97%的患者有急性喉损伤,其中88%为严重损伤。红斑是最常见的损伤形式。插管持续时间平均为4.5天,与声门下狭窄的关联呈显著趋势(p = 0.06)。带套囊和不带套囊的导管导致的喉损伤相似。受试者年龄、导管尺寸和插管者技术水平与喉损伤无关。18%的患者因拔管后喉部病变需要干预。三名(10%)儿童拔管后出现喘鸣,其中两名需要手术干预(6%)。
拔管后喉损伤并不少见。纤维内镜检查是一种用于床边评估小儿喉部插管后状况的廉价且具有成本效益的工具。儿童插管后喉损伤的早期诊断可预防长期后遗症。因此,小儿人群应常规进行拔管后纤维喉镜检查。