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小脑回路血管病变后的运动障碍。

Movement Disorders Following Cerebrovascular Lesions in Cerebellar Circuits.

机构信息

Department of Neurology, Chonnam National University Medical School, Gwangju, Korea.

出版信息

J Mov Disord. 2016 May;9(2):80-8. doi: 10.14802/jmd.16004. Epub 2016 May 25.

Abstract

Cerebellar circuitry is important to controlling and modifying motor activity. It conducts the coordination and correction of errors in muscle contractions during active movements. Therefore, cerebrovascular lesions of the cerebellum or its pathways can cause diverse movement disorders, such as action tremor, Holmes' tremor, palatal tremor, asterixis, and dystonia. The pathophysiology of abnormal movements after stroke remains poorly understood. However, due to the current advances in functional neuroimaging, it has recently been described as changes in functional brain networks. This review describes the clinical features and pathophysiological mechanisms in different types of movement disorders following cerebrovascular lesions in the cerebellar circuits.

摘要

小脑的电路对于控制和调整运动活动非常重要。它在主动运动时协调和纠正肌肉收缩中的错误。因此,小脑或其通路的脑血管病变可导致多种运动障碍,如动作震颤、霍姆斯震颤、腭震颤、舞蹈手足徐动症和肌张力障碍。中风后异常运动的病理生理学仍知之甚少。然而,由于目前功能神经影像学的进展,最近已将其描述为功能性脑网络的变化。本综述描述了小脑回路中脑血管病变后不同类型运动障碍的临床特征和病理生理机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/920c/4886204/c8fbab2bf534/jmd-16004f1.jpg

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