Toguzov R T, Korochkin I M, Tikhonov Iu V, Novikova T E, Pimenov A M
Kardiologiia. 1989 Feb;29(2):57-60.
Venous blood acid-soluble fraction was investigated by means of high-efficiency liquid chromatography in patients with myocardial infarction and angina pectoris. Myocardial ischemia is shown to result in marked changes of purine and pyrimidine metabolism. A rise in intermediate and end products of purine metabolism (inosine, hypoxanthine, xanthine, uric acid), and the emergence of thymin and thymidine were demonstrated in venous blood of patients with myocardial infarction and angina pectoris.
采用高效液相色谱法对心肌梗死和心绞痛患者的静脉血酸溶性成分进行了研究。结果表明，心肌缺血会导致嘌呤和嘧啶代谢发生显著变化。在心肌梗死和心绞痛患者的静脉血中，嘌呤代谢的中间产物和终产物（肌苷、次黄嘌呤、黄嘌呤、尿酸）有所增加，并且出现了胸腺嘧啶和胸腺嘧啶核苷。
