Shimelis I V, Prevarskiĭ B P, Zazimko R N, Khaliavko I G, Pavlovskaia L R
Kardiologiia. 1989 Feb;29(2):67-70.
Cardiovascular response to isometric stress (IS) applied to the upper and the lower extremities, and general isometric stress amounting to 30% of the maximum productive force (MPF) were compared in 50 normal subjects and 60 coronary patients. Hemodynamic values were significantly higher at 30% MPF general isometric stress tolerance threshold, as compared to those seen in the last minute of the maintenance of IS of the same force by the upper extremities. Hemodynamic responses to IS, applied to the lower extremities, and to general 30% MPF isometric stress were basically similar. The general 30% MPF isometric stress was more sensitive with respect to the diagnosis of coronary disease, while the test's specificity and predictive value were fairly high. The sensitivity of the lower-extremity IS test was somewhat lower, as compared to that of the general isometric stress test, yet it is much higher, as compared to the upper-extremity IS test, and can therefore be used in screening programs.
对50名正常受试者和60名冠心病患者比较了对施加于上肢和下肢的等长应激（IS）以及相当于最大生产力（MPF）30%的全身性等长应激的心血管反应。与上肢以相同力量维持IS的最后一分钟相比，在30%MPF全身性等长应激耐受阈值时的血流动力学值显著更高。对施加于下肢的IS以及全身性30%MPF等长应激的血流动力学反应基本相似。全身性30%MPF等长应激对冠心病的诊断更敏感，而该测试的特异性和预测价值相当高。与全身性等长应激测试相比，下肢IS测试的敏感性略低，但与上肢IS测试相比则高得多，因此可用于筛查项目。
