Vasilenko Iu V, Karalkin A V, Konstantinova G D
Khirurgiia (Mosk). 1989 Mar(3):52-6.
From the results of examination of 91 patients with postthrombotic disease by radioindication methods the authors established that blood filling of the lower limbs increases in a horizontal position. Varicosity leads to further growth of regional blood volumes (RBV). No essential difference was revealed in blood filling in the recanalized and mixed forms of the postthrombotic disease. The increase of blood volume as compared to the initial value in these patients in an orthostatic position is below normal. Storage of blood in the lower limbs causes increase of the circulating volume (CV) at first, but after 5 years of the disease it leads to gradual reduction of the CV and increase of RBV. Excessive blood filling in the postthrombotic disease causes diminution of the resilient-elastic properties of the vein, makes the work of the muscular-venous pump of the leg difficult, and leads to microcirculatory disorders. Combined treatment for the purpose of removing the principal links of the pathogenesis is suggested.
通过放射性指示方法对91例血栓形成后疾病患者的检查结果，作者确定下肢的血液充盈在水平位时会增加。静脉曲张会导致局部血容量（RBV）进一步增加。在血栓形成后疾病的再通型和混合型中，血液充盈情况未显示出本质差异。与初始值相比，这些患者在直立位时血容量的增加低于正常水平。下肢血液储存起初会导致循环血量（CV）增加，但在患病5年后会导致CV逐渐减少和RBV增加。血栓形成后疾病中的过度血液充盈会导致静脉弹性特性降低，使腿部肌肉-静脉泵的工作困难，并导致微循环障碍。建议采取联合治疗以消除发病机制的主要环节。
