Schmidt C
Secteur d'angiologie, hôpital central, centre hospitalier universitaire de Nancy.
Rev Prat. 1994 Mar 15;44(6):745-50.
Venous post-thrombotic disease is a common complication of deep venous thrombosis of the lower limbs. Prevalence is around 75% after a five-year follow-up and 25% of these patients suffer from severe disorders. The clinical symptoms are non-specific and begin months or years after the acute thrombosis. The patients' claims range from uncomplicated oedema, leg cramps and superficial varicose veins to permanent skin changes (dermatitis, hypodermatitis, leg ulcers). Functional vascular exploration (continuous-wave Doppler, plethysmography, pulsed-wave echo-Doppler, exceptionally venography) allows a better knowledge of the haemodynamic consequences of the post-thrombotic disease: deep persistent truncular obstruction, partial or total recanalization, valvular incompetence and reflux in the deep veins, superficial varicose veins, incompetence of the perforating veins in the gaiter area, failure of the calf venous pump and microangiopathy.
静脉血栓形成后疾病是下肢深静脉血栓形成的常见并发症。五年随访后的患病率约为75%，其中25%的患者患有严重疾病。临床症状不具特异性，在急性血栓形成数月或数年之后出现。患者的症状表现多样，从不复杂的水肿、腿部痉挛和浅静脉曲张到永久性皮肤改变（皮炎、皮下组织炎、腿部溃疡）。功能性血管检查（连续波多普勒、体积描记法、脉冲波回声多普勒，偶尔进行静脉造影）有助于更好地了解血栓形成后疾病的血流动力学后果：深部持续性主干阻塞、部分或完全再通、深静脉瓣膜功能不全和反流、浅静脉曲张、袜套区穿通静脉功能不全、小腿静脉泵功能衰竭和微血管病变。
