紫外线照射后二氧化钛对牙周病原体的抗菌作用
Antimicrobial effect of titanium dioxide after ultraviolet irradiation against periodontal pathogen.
作者信息
Shirai Ryo, Miura Tadashi, Yoshida Ayaka, Yoshino Fumihiko, Ito Taichi, Yoshinari Masao, Yajima Yasutomo
机构信息
Department of Oral and Maxillofacial Implantology, Tokyo Dental College.
出版信息
Dent Mater J. 2016;35(3):511-6. doi: 10.4012/dmj.2015-406.
We focused on the antimicrobial effects of titanium dioxide (TiO2) after stopping ultraviolet (UV) irradiation as an adjunctive treatment for peri-implantitis in this study. The aim was to determine the continuous photocatalytic effects of TiO2 after UV irradiation and its antimicrobial activity against periodontal pathogen. The continuous photocatalytic effects of TiO2 after UV irradiation were determined by electron spin resonance (ESR) spectroscopy using TiO2 particles of various sizes with various UV irradiation times. In addition, antimicrobial activity against Porphyromonas gingivalis was investigated by quantitation of colony-forming units (CFUs). The results showed that the ESR signal ratio for the UV-irradiated TiO2 was significantly higher than that of the non-irradiated TiO2. UV-irradiated TiO2 significantly reduced the number of P. gingivalis when compared with non-irradiated controls. These results suggest that TiO2 has a continuous photocatalytic effect even after stopping UV irradiation and that it showed antimicrobial activity against periodontal pathogen.
在本研究中，我们将停止紫外线（UV）照射后二氧化钛（TiO₂）的抗菌作用作为种植体周围炎的辅助治疗方法进行了重点研究。目的是确定紫外线照射后TiO₂的持续光催化作用及其对牙周病原体的抗菌活性。使用不同尺寸的TiO₂颗粒并进行不同时间的紫外线照射，通过电子自旋共振（ESR）光谱法测定紫外线照射后TiO₂的持续光催化作用。此外，通过定量菌落形成单位（CFU）研究了对牙龈卟啉单胞菌的抗菌活性。结果表明，紫外线照射的TiO₂的ESR信号比明显高于未照射的TiO₂。与未照射的对照相比，紫外线照射的TiO₂显著减少了牙龈卟啉单胞菌的数量。这些结果表明，即使停止紫外线照射，TiO₂仍具有持续的光催化作用，并且对牙周病原体显示出抗菌活性。
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