一种能识别5-甲基胞嘧啶残基的植物DNA结合蛋白。
A plant DNA-binding protein that recognizes 5-methylcytosine residues.
作者信息
Zhang D L, Ehrlich K C, Supakar P C, Ehrlich M
机构信息
Southern Regional Research Center, U.S. Department of Agriculture, New Orleans, Louisiana 70179.
出版信息
Mol Cell Biol. 1989 Mar;9(3):1351-6. doi: 10.1128/mcb.9.3.1351-1356.1989.
Abstract
A novel, 5-methylcytosine-specific, DNA-binding protein, DBP-m, has been identified in nuclear extracts of peas. DBP-m specifically recognizes 5-methylcytosine residues in DNA without appreciable DNA sequence specificity, unlike a mammalian DNA-binding protein (MDBP), which recognizes 5-methylcytosine residues but only in a related family of 14-base-pair sequences.
摘要
在豌豆的核提取物中发现了一种新型的、具有5-甲基胞嘧啶特异性的DNA结合蛋白DBP-m。与哺乳动物的DNA结合蛋白（MDBP）不同，DBP-m能特异性识别DNA中的5-甲基胞嘧啶残基，且对DNA序列没有明显的特异性，而MDBP只能在一个由14个碱基对组成的相关序列家族中识别5-甲基胞嘧啶残基。
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