6-磷酸果糖天冬氨酸及一些相关阿玛多利化合物的合成。
Synthesis of 6-phosphofructose aspartic acid and some related Amadori compounds.
作者信息
Hansen Alexandar L, Behrman Edward J
机构信息
Campus Chemical Instrument Center, The Ohio State University, 496 W. 12th Avenue, Columbus, OH 43210, USA.
Department of Chemistry & Biochemistry, The Ohio State University, 484 W. 12th Avenue, Columbus, OH 43210, USA.
出版信息
Carbohydr Res. 2016 Aug 5;431:1-5. doi: 10.1016/j.carres.2016.05.003. Epub 2016 May 14.
Abstract
We describe the synthesis and characterization of 6-phosphofructose-aspartic acid, an intermediate in the metabolism of fructose-asparagine by Salmonella. We also report improved syntheses of fructose-asparagine itself and of fructose-aspartic acid.
摘要
我们描述了6-磷酸果糖-天冬氨酸的合成与表征，它是沙门氏菌代谢果糖-天冬酰胺过程中的一种中间体。我们还报告了果糖-天冬酰胺本身以及果糖-天冬氨酸合成方法的改进。
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本文引用的文献
1
Fructose-asparagine is a primary nutrient during growth of Salmonella in the inflamed intestine.果糖天冬酰胺是沙门氏菌在发炎肠道中生长期间的一种主要营养物质。
PLoS Pathog. 2014 Jun 26;10(6):e1004209. doi: 10.1371/journal.ppat.1004209. eCollection 2014 Jun.
2
1-Amino-1-deoxy-D-fructose ("fructosamine") and its derivatives.1-氨基-1-脱氧-D-果糖（“果糖胺”）及其衍生物。
Adv Carbohydr Chem Biochem. 2010;64:291-402. doi: 10.1016/S0065-2318(10)64006-1.
3
The CLIP/CLAP-HSQC: pure absorptive spectra for the measurement of one-bond couplings.CLIP/CLAP-HSQC：用于测量一键耦合的纯吸收光谱。
J Magn Reson. 2008 Jun;192(2):314-22. doi: 10.1016/j.jmr.2008.03.009. Epub 2008 Mar 21.
4
Stereoselective synthesis of natural N-(1-Deoxy-D-beta-fructos-1-yl)-L-amino acids and their effect on lead decorporation.天然N-(1-脱氧-D-β-果糖-1-基)-L-氨基酸的立体选择性合成及其对铅促排的作用
Chem Res Toxicol. 2004 Aug;17(8):1112-20. doi: 10.1021/tx034223p.
5
Mid-infrared spectroscopic measurement of ionic dissociative materials in the metabolic pathway.代谢途径中离子解离材料的中红外光谱测量。
Appl Spectrosc. 2003 Dec;57(12):1510-6. doi: 10.1366/000370203322640152.
6
NMRPipe: a multidimensional spectral processing system based on UNIX pipes.NMRPipe：一个基于UNIX管道的多维光谱处理系统。
J Biomol NMR. 1995 Nov;6(3):277-93. doi: 10.1007/BF00197809.
7
[Quantitative investigation of the reaction of hexoses with amino acids].[己糖与氨基酸反应的定量研究]
Justus Liebigs Ann Chem. 1967 Apr;703:202-14. doi: 10.1002/jlac.19677030124.
8
Enzyme kinetics in solvents of increased viscosity. Dynamic aspects of carbonic anhydrase catalysis.
Biochemistry. 1987 May 5;26(9):2597-606. doi: 10.1021/bi00383a028.
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