Meregalli M, Antoniazzi V, Torchio G, Colombo E, Bocchi M, Sonzini E, Lino S
U.S.S.L. n. 67, Ospedale S. Corona, Garbagnate Milanese.
Minerva Med. 1989 Apr;80(4):345-7.
Radioimmunology was used to measure serum levels of CEA (carcinoembryonic antigen) in 108 patients with a variety of different advanced malignant neoplasms and in a control group of 60 healthy subjects. TPA proved more sensitive as a tumour marker than CEA, since increased TPA was found in 76% of the cancer cases compared to 42% for CEA. No significant increase in diagnostic sensitivity was obtained by using both markers rather than PTA alone.
采用放射免疫法检测了108例患有各种不同晚期恶性肿瘤的患者以及60名健康对照者血清中的癌胚抗原（CEA）水平。组织多肽抗原（TPA）作为一种肿瘤标志物比CEA更敏感，因为在76%的癌症病例中发现TPA升高，而CEA升高的病例为42%。同时使用这两种标志物而非仅使用TPA，并未显著提高诊断敏感性。
