Song Xiaochen, Zhu Lan, Ding Jing, Xu Tao, Lang Jinghe
Department of Gynecology and Obstetrics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Department of Gynecology and Obstetrics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Int J Gynaecol Obstet. 2016 Sep;134(3):252-5. doi: 10.1016/j.ijgo.2016.02.015. Epub 2016 May 19.
To describe the anatomic variety of congenital cervical atresia and to explore the relationship between this disorder and pelvic endometriosis.
In a retrospective study, records were reviewed for 96 patients with a confirmed diagnosis of congenital cervical atresia treated at a center in Beijing, China, between January 1984 and October 2014. Data on demographic parameters, symptoms, anatomic features, and endometriosis were obtained and analyzed.
Of the 96 patients, 54 (56%) had pelvic endometriosis, 23 (24%) had a uterine malformation, 75 (78%) had a vaginal malformation, and 12 (13%) had a urinary malformation. The patients with a delay from first symptoms to surgery of more than 1year had a higher incidence of endometriosis than did those with a delay of 1year or less (45/71 [63%] vs 7/23 [30%]; P=0.006), and this trend was not related to the severity of endometriosis (P=0.658). Among the 31 patients with unilateral endometrial cysts, 20 (65%) had left-sided cysts and 11 (35%) had right-sided cysts (P=0.005).
More than half of patients with congenital cervical atresia had pelvic endometriosis. Early diagnosis and surgery seem to be necessary to prevent endometriosis among patients with congenital cervical atresia.
描述先天性宫颈闭锁的解剖学变异，并探讨该疾病与盆腔子宫内膜异位症之间的关系。
在一项回顾性研究中，对1984年1月至2014年10月在中国北京某中心接受治疗的96例确诊为先天性宫颈闭锁的患者的记录进行了回顾。获取并分析了有关人口统计学参数、症状、解剖特征和子宫内膜异位症的数据。
96例患者中，54例（56%）患有盆腔子宫内膜异位症，23例（24%）有子宫畸形，75例（78%）有阴道畸形，12例（13%）有泌尿系统畸形。首次出现症状至手术延迟超过1年的患者子宫内膜异位症的发生率高于延迟1年或更短时间的患者（45/71 [63%] 对7/23 [30%]；P = 0.006），且这种趋势与子宫内膜异位症的严重程度无关（P = 0.658）。在31例单侧子宫内膜囊肿患者中，20例（65%）为左侧囊肿，11例（35%）为右侧囊肿（P = 0.005）。
超过一半的先天性宫颈闭锁患者患有盆腔子宫内膜异位症。早期诊断和手术似乎对于预防先天性宫颈闭锁患者的子宫内膜异位症是必要的。
