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一项关于血管腔内主动脉修复术后II型内漏的介入放射学多机构调查:日本腔内金属支架与移植物学会的问卷调查结果

A multi-institutional survey of interventional radiology for type II endoleaks after endovascular aortic repair: questionnaire results from the Japanese Society of Endoluminal Metallic Stents and Grafts in Japan.

作者信息

Ogawa Yukihisa, Nishimaki Hiroshi, Osuga Keigo, Ikeda Osamu, Hongo Norio, Iwakoshi Shinichi, Kawasaki Ryota, Woodhams Reiko, Yamaguchi Masato, Kamiya Mika, Kanematsu Masayuki, Honda Masanori, Kaminou Toshio, Koizumi Jun, Kichikawa Kimihiko

机构信息

Department of Radiology, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki, 216-8511, Japan.

Department of Cardiovascular Surgery, St. Marianna University School of Medicine, Kawasaki, Japan.

出版信息

Jpn J Radiol. 2016 Aug;34(8):564-71. doi: 10.1007/s11604-016-0558-y. Epub 2016 Jun 4.

Abstract

PURPOSE

To investigate the current status of interventional radiology (IR) procedures for a type II endoleak (T2EL) in Japan, and to identify the technical aspects that affect treatment results.

MATERIALS AND METHODS

A retrospective survey was conducted by distributing questionnaires to 25 institutions. The eligibility criteria were endovascular aortic repair (EVAR) performed using commercial stent grafts and IR performed for T2EL between January 2007 and December 2013. Technical success was defined as disappearance of the EL on digital subtraction angiography immediately after embolization, and imaging success was defined as no EL on contrast-enhanced computed tomography within 6 months. Statistical comparisons of the number of involved branches, embolization level, embolic material, and changes in aneurysm size were made between the imaging success and imaging failure groups. The technical and imaging success rates were also compared between the initial therapy and repeat groups.

RESULTS

A total of 166 cases were investigated. Initial therapy was performed in 147 cases (88.6 %), with repeat therapy in 19 cases (11.4 %). Transcatheter arterial embolization (TAE) was used most frequently, in 161 cases (97 %), with direct puncture (DP) used in 5 cases (3 %). Both coil embolization for the branches and NBCA embolization for the sac were frequently chosen. The technical success rate was 83.2 % (TAE group), and the imaging success rate was 46.5 % (TAE + DP groups). Branch + sac embolization was performed more frequently in the imaging success group. There was no significant difference in the number of involved branches or embolic material between the imaging success and imaging failure groups. Enlargement of the aneurysm was more frequently seen in the imaging failure group. There were no significant differences in the technical success and imaging success rates between the initial therapy and repeat groups.

CONCLUSION

This is the first report of a multi-institutional questionnaire survey of IR procedures for T2EL after EVAR in Japan that was conducted to determine the current status. Enlargement of aneurysm size after embolization was more frequently seen in the imaging failure group. It is important to embolize both branch and sac to achieve imaging success, regardless of embolic material. Long-term outcomes need to be investigated.

摘要

目的

调查日本II型内漏(T2EL)介入放射学(IR)治疗的现状,并确定影响治疗效果的技术因素。

材料与方法

通过向25家机构发放问卷进行回顾性调查。纳入标准为2007年1月至2013年12月期间使用商用支架型人工血管进行的血管腔内主动脉修复术(EVAR)以及针对T2EL进行的IR治疗。技术成功定义为栓塞后数字减影血管造影显示内漏消失,影像成功定义为6个月内增强CT扫描未见内漏。对影像成功组和影像失败组的受累分支数量、栓塞水平、栓塞材料以及动脉瘤大小变化进行统计学比较。同时比较初始治疗组和重复治疗组的技术成功率和影像成功率。

结果

共调查166例病例。147例(88.6%)进行了初始治疗,19例(11.4%)进行了重复治疗。最常采用经导管动脉栓塞术(TAE),共161例(97%),5例(3%)采用直接穿刺(DP)。分支弹簧圈栓塞和瘤腔NBCA栓塞均较为常用。技术成功率为83.2%(TAE组),影像成功率为46.5%(TAE + DP组)。影像成功组更常采用分支+瘤腔栓塞。影像成功组和影像失败组在受累分支数量或栓塞材料方面无显著差异。影像失败组动脉瘤增大更为常见。初始治疗组和重复治疗组在技术成功率和影像成功率方面无显著差异。

结论

这是日本首次针对EVAR术后T2EL的IR治疗进行多机构问卷调查以确定现状的报告。影像失败组栓塞后动脉瘤增大更为常见。无论栓塞材料如何,对分支和瘤腔均进行栓塞对于实现影像成功很重要。需要对长期疗效进行研究。

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