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[Pharmacology of azidomorphine].

作者信息

Bulaev V M, Zakusov V V, Knoll Zh, Chichenkov O N

出版信息

Biull Eksp Biol Med. 1978 Jun;85(6):685-8.

PMID:27263
Abstract

As revealed, in acute experiments on rabbits, cats, and rats, a new morphine-like synthetic analgesic drug azidomorphine exceeded 20--100-fold the morphine ability to inhibit synaptic transmission in the thalamic structures, cerebral cortex, and the spinal cord during the nociceptive stimulation, and also by its analgesic activity.

摘要

相似文献

1
[Pharmacology of azidomorphine].
Biull Eksp Biol Med. 1978 Jun;85(6):685-8.
2
[Effect of morphine and azidomorphine on the neuronal activity of the cerebral cortex].[吗啡和叠氮吗啡对大脑皮质神经元活动的影响]
Biull Eksp Biol Med. 1977 Jun;83(6):698-9.
3
Comparison of the antinociceptive effect of acute morphine in female and male Sprague-Dawley rats using the long-lasting mu-antagonist methocinnamox.使用长效μ-拮抗剂美索辛胺比较急性吗啡对雌性和雄性Sprague-Dawley大鼠的镇痛作用。
Brain Res. 2005 Oct 5;1058(1-2):137-47. doi: 10.1016/j.brainres.2005.07.060. Epub 2005 Sep 1.
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The effects of microinjection of morphine into thalamic nucleus submedius on formalin-evoked nociceptive responses of neurons in the rat spinal dorsal horn.向大鼠丘脑正中核微量注射吗啡对福尔马林诱发的脊髓背角神经元伤害性反应的影响。
Neurosci Lett. 2006 Jun 19;401(1-2):103-7. doi: 10.1016/j.neulet.2006.02.075. Epub 2006 Mar 23.
5
Investigations of the analgesic and morphine-like properties of azidomorphine.叠氮吗啡的镇痛及类吗啡特性研究。
J Pharmacol Exp Ther. 1977 Jun;201(3):580-6.
6
[Morphine-like activity of the enkephalin analog Tyr-D-Ala-Gly-Phe-NH2].[脑啡肽类似物酪氨酸-天冬氨酸-甘氨酸-苯丙氨酸-酰胺的类吗啡活性]
Biull Eksp Biol Med. 1981 Feb;91(2):171-3.
7
Peripheral versus central antinociceptive actions of 6-amino acid-substituted derivatives of 14-O-methyloxymorphone in acute and inflammatory pain in the rat.14-O-甲基羟吗啡酮的6-氨基酸取代衍生物在大鼠急性和炎性疼痛中的外周与中枢抗伤害感受作用
J Pharmacol Exp Ther. 2005 Feb;312(2):609-18. doi: 10.1124/jpet.104.075176. Epub 2004 Sep 21.
8
[Effect of narcotic analgesics on excitatory transmission in the spinal cord].
Biull Eksp Biol Med. 1978 Feb;85(2):182-5.
9
Effects of opiate agonists and antagonists on central neurons of the cat.阿片类激动剂和拮抗剂对猫中枢神经元的作用。
J Pharmacol Exp Ther. 1976 Jan;196(1):107-20.
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[Effect of narcotic analgesics of nociceptive transmission in the spinal cord].[麻醉性镇痛药对脊髓伤害性信息传递的影响]
Farmakol Toksikol. 1982 Mar-Apr;45(2):30-5.

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