Bulaev V M, Chichenkov O N
Biull Eksp Biol Med. 1977 Jun;83(6):698-9.
Acute experiments were conducted on unanesthetized curare-treated cats and rats. Analgetic doses of morphine and azidomorphine proved to depress the spontaneous and bradykinin-induced neuronal activity in the sensory-motor zone of the cerebral cortex. The inhibiting effect of the drugs was eliminated by nalorphine. It is supposed that the depressive action of morphine and azidomorphine may be connected with their direct influence on the cerebral cortex.
在未麻醉的经箭毒处理的猫和大鼠身上进行了急性实验。镇痛剂量的吗啡和叠氮吗啡被证明可抑制大脑皮质感觉运动区的自发和缓激肽诱导的神经元活动。纳洛芬可消除这些药物的抑制作用。据推测，吗啡和叠氮吗啡的抑制作用可能与其对大脑皮质的直接影响有关。
