与言语失用症相关的脑损伤：来自病例研究的证据。
Brain damage associated with apraxia of speech: evidence from case studies.
作者信息
Moser Dana, Basilakos Alexandra, Fillmore Paul, Fridriksson Julius
机构信息
a Department of Communication Sciences and Disorders , University of New Hampshire , Durham , NH , USA.
b Department of Communication Sciences and Disorders , University of South Carolina , Columbia , SC , USA.
出版信息
Neurocase. 2016 Aug;22(4):346-56. doi: 10.1080/13554794.2016.1172645. Epub 2016 Jun 5.
Abstract
The site of crucial damage that causes acquired apraxia of speech (AOS) has been debated in the literature. This study presents five in-depth cases that offer insight into the role of brain areas involved in AOS. Four of the examined participants had a primary impairment of AOS either with (n = 2) or without concomitant mild aphasia (n = 2). The fifth participant presented with a lesion relatively isolated to the left anterior insula (AIns-L), damage that is rarely reported in the literature, but without AOS. Taken together, these cases challenge the role of the AIns-L and implicate the left motor regions in AOS.
摘要
导致后天性言语失用症（AOS）的关键损伤部位在文献中一直存在争议。本研究展示了五个深入的案例，这些案例有助于深入了解参与AOS的脑区所起的作用。四名被检查的参与者患有原发性AOS损伤，其中两名伴有轻度失语症，另外两名不伴有轻度失语症。第五名参与者的病变相对局限于左侧前岛叶（AIns-L），这种损伤在文献中很少有报道，但该参与者没有AOS。综合来看，这些案例对AIns-L的作用提出了质疑，并表明左侧运动区域与AOS有关。
相似文献
1
Brain damage associated with apraxia of speech: evidence from case studies.
Neurocase. 2016 Aug;22(4):346-56. doi: 10.1080/13554794.2016.1172645. Epub 2016 Jun 5.
2
Patterns of poststroke brain damage that predict speech production errors in apraxia of speech and aphasia dissociate.
Stroke. 2015 Jun;46(6):1561-6. doi: 10.1161/STROKEAHA.115.009211. Epub 2015 Apr 23.
3
Altered resting-state network connectivity in stroke patients with and without apraxia of speech.
Neuroimage Clin. 2015 Mar 25;8:429-39. doi: 10.1016/j.nicl.2015.03.013. eCollection 2015.
4
Clinical and anatomical correlates of apraxia of speech.
Brain Lang. 2006 Jun;97(3):343-50. doi: 10.1016/j.bandl.2006.01.008. Epub 2006 Mar 6.
5
Apraxia of speech: concepts and controversies.
J Speech Lang Hear Res. 2012 Oct;55(5):S1485-501. doi: 10.1044/1092-4388(2012/12-0128).
6
Damage to the Left Precentral Gyrus Is Associated With Apraxia of Speech in Acute Stroke.
Stroke. 2016 Jan;47(1):31-6. doi: 10.1161/STROKEAHA.115.010402. Epub 2015 Dec 8.
7
Speech motor programming in apraxia of speech: evidence from a delayed picture-word interference task.
Am J Speech Lang Pathol. 2013 May;22(2):S380-96. doi: 10.1044/1058-0360(2013/12-0101).
8
The neuroanatomy of pure apraxia of speech in stroke.
Brain Lang. 2014 Feb;129:43-6. doi: 10.1016/j.bandl.2014.01.004. Epub 2014 Feb 18.
9
Tractography of supplementary motor area projections in progressive speech apraxia and aphasia.
Neuroimage Clin. 2022;34:102999. doi: 10.1016/j.nicl.2022.102999. Epub 2022 Mar 30.
10
Examining speech motor planning difficulties in apraxia of speech and aphasia via the sequential production of phonetically similar words.
Cogn Neuropsychol. 2021 Feb;38(1):72-87. doi: 10.1080/02643294.2020.1847059. Epub 2020 Nov 29.
引用本文的文献
1
A Novel Candidate Neuromarker of Central Motor Dysfunction in Childhood Apraxia of Speech.
J Neurosci. 2025 May 7;45(19):e1471242025. doi: 10.1523/JNEUROSCI.1471-24.2025.
2
Decoding speech intent from non-frontal cortical areas.
J Neural Eng. 2025 Feb 13;22(1):016024. doi: 10.1088/1741-2552/adaa20.
3
Four dimensions of naturalistic language production in aphasia after stroke.
Brain. 2025 Jan 7;148(1):291-312. doi: 10.1093/brain/awae195.
4
The Apraxia of Speech Rating Scale: Reliability, Validity, and Utility.
Am J Speech Lang Pathol. 2023 Mar 9;32(2):469-491. doi: 10.1044/2022_AJSLP-22-00148. Epub 2023 Jan 11.
5
A Neurosurgical Functional Dissection of the Middle Precentral Gyrus during Speech Production.
J Neurosci. 2022 Nov 9;42(45):8416-8426. doi: 10.1523/JNEUROSCI.1614-22.2022.
6
Alteration of network connectivity in stroke patients with apraxia of speech after tDCS: A randomized controlled study.
Front Neurol. 2022 Sep 15;13:969786. doi: 10.3389/fneur.2022.969786. eCollection 2022.
7
Loss of cGMP-dependent protein kinase II alters ultrasonic vocalizations in mice, a model for speech impairment in human microdeletion 4q21 syndrome.
Neurosci Lett. 2021 Aug 10;759:136048. doi: 10.1016/j.neulet.2021.136048. Epub 2021 Jun 12.
8
Modelling speech motor programming and apraxia of speech in the DIVA/GODIVA neurocomputational framework.
Aphasiology. 2021;35(4):424-441. doi: 10.1080/02687038.2020.1765307. Epub 2020 May 18.
9
Recovery of Apraxia of Speech and Aphasia in Patients With Hand Motor Impairment After Stroke.
Front Neurol. 2021 Mar 31;12:634065. doi: 10.3389/fneur.2021.634065. eCollection 2021.
10
Effects of tDCS on Sound Duration in Patients with Apraxia of Speech in Primary Progressive Aphasia.
Brain Sci. 2021 Mar 6;11(3):335. doi: 10.3390/brainsci11030335.
本文引用的文献
1
Patterns of poststroke brain damage that predict speech production errors in apraxia of speech and aphasia dissociate.
Stroke. 2015 Jun;46(6):1561-6. doi: 10.1161/STROKEAHA.115.009211. Epub 2015 Apr 23.
2
Partially overlapping sensorimotor networks underlie speech praxis and verbal short-term memory: evidence from apraxia of speech following acute stroke.
Front Hum Neurosci. 2014 Aug 25;8:649. doi: 10.3389/fnhum.2014.00649. eCollection 2014.
3
The Apraxia of Speech Rating Scale: a tool for diagnosis and description of apraxia of speech.
J Commun Disord. 2014 Sep-Oct;51:43-50. doi: 10.1016/j.jcomdis.2014.06.008. Epub 2014 Jul 14.
4
Toward an Integrated Psycholinguistic, Neurolinguistic, Sensorimotor Framework for Speech Production.
Lang Cogn Process. 2014 Jan 1;29(1):52-59. doi: 10.1080/01690965.2013.852907.
5
The neuroanatomy of pure apraxia of speech in stroke.
Brain Lang. 2014 Feb;129:43-6. doi: 10.1016/j.bandl.2014.01.004. Epub 2014 Feb 18.
6
Development of insula connectivity between ages 12 and 30 revealed by high angular resolution diffusion imaging.
Hum Brain Mapp. 2014 Apr;35(4):1790-800. doi: 10.1002/hbm.22292. Epub 2013 Jul 8.
7
Chronic apraxia of speech and Broca's area.
Stroke. 2013 Mar;44(3):740-4. doi: 10.1161/STROKEAHA.112.678508. Epub 2013 Jan 29.
8
Neuroimaging comparison of primary progressive apraxia of speech and progressive supranuclear palsy.
Eur J Neurol. 2013 Apr;20(4):629-37. doi: 10.1111/ene.12004. Epub 2012 Oct 18.
9
Re-establishing Broca's initial findings.
Brain Lang. 2012 Nov;123(2):125-30. doi: 10.1016/j.bandl.2012.08.007. Epub 2012 Oct 8.
10
The diagnosis and understanding of apraxia of speech: why including neurodegenerative etiologies may be important.
J Speech Lang Hear Res. 2012 Oct;55(5):S1518-22. doi: 10.1044/1092-4388(2012/11-0309).
Zotero 插件