Dacey D M, Grossman S P
Physiol Behav. 1977 Sep;19(3):389-95. doi: 10.1016/0031-9384(77)90284-0.
Small bilateral electrolytic lesions confined to the region of the central nuclei of the amygdala failed to affect food and water consumption in male rats. More medially-placed lesions which damaged portions of the internal capsule, entopeduncular nucleus and globus pallidus adjacent to the central nucleus produced transient aphagia and adipsia accompanied by sensory-motor impairments that interfered with the act of feeding, as evidenced by a large postoperative increase in the amount of food spilled. In some cases lesions restricted to the internal capsule and entopeduncular nucleus produced these sensory-motor deficits but no aphagia or adipsia. Small lesions damaging primarily ventral portions of the posteromedial pallidi resulted in aphagia and adipsia but no apparent sensory-motor impairment. The results indicate that at least two, possibly independent, deficits in food intake may be produced by lesions in the immediate area of the dorsomedial amygdala. It is suggested that the effects on ingestive behavior which several investigators have observed in rats with dorsomedial amygdaloid damage may in fact be due to incidental destruction of adjacent tissues.
局限于杏仁核中央核区域的双侧小电解损伤并未影响雄性大鼠的食物和水消耗。更靠内侧的损伤破坏了内囊、脚内核以及与中央核相邻的苍白球部分，导致短暂的摄食和饮水减少，并伴有感觉运动障碍，干扰了进食行为，术后食物洒落量大幅增加就证明了这一点。在某些情况下，局限于内囊和脚内核的损伤会产生这些感觉运动缺陷，但不会导致摄食和饮水减少。主要损害后内侧苍白球腹侧部分的小损伤会导致摄食和饮水减少，但没有明显的感觉运动障碍。结果表明，背内侧杏仁核紧邻区域的损伤可能产生至少两种可能独立的食物摄入缺陷。有人提出，几位研究人员在背内侧杏仁核损伤的大鼠中观察到的对摄食行为的影响，实际上可能是由于相邻组织的意外破坏所致。
