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雅司病:朝着世界卫生组织的根除目标迈进。

Yaws: towards the WHO eradication target.

作者信息

Marks Michael

机构信息

Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, Keppel Street, London, WC1E 7HT, UK; Hospital for Tropical Diseases, University College London Hospitals NHS Trust, London, WC1E 6JB, UK

出版信息

Trans R Soc Trop Med Hyg. 2016 Jun;110(6):319-20. doi: 10.1093/trstmh/trw032. Epub 2016 Jun 6.

Abstract

In 2012 WHO declared a target to eradicate yaws by 2020. The cornerstone of this strategy is community mass treatment with azithromycin. Initial studies suggest this is a very effective tool that may be capable of interrupting transmission. Alongside this there has been progress in the development and validation of diagnostic tests for yaws. Several new challenges have also emerged, in particular, evidence that Haemophilus ducreyi can cause phenotypically similar ulcers in yaws endemic communities, and evidence for a possible non-human primate reservoir. The 2020 eradication target remains ambitious and more challenges should be expected on the journey.

摘要

2012年,世界卫生组织宣布了到2020年根除雅司病的目标。该战略的基石是用阿奇霉素进行社区群体治疗。初步研究表明,这是一种非常有效的工具,可能能够阻断传播。与此同时,雅司病诊断检测方法的开发和验证也取得了进展。还出现了一些新的挑战,特别是有证据表明,杜克雷嗜血杆菌可在雅司病流行社区引起表型相似的溃疡,以及存在可能的非人灵长类动物宿主的证据。2020年的根除目标仍然雄心勃勃,在这一进程中预计还会有更多挑战。

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