Rivas de la Lastra E, Sagel E, Acevedo D, Arias J, Sierra I
Rev Med Panama. 1989 Jan;14(1):38-43.
The authors present the clinical history of the first case of benign hemophagocytic syndrome diagnosed in Panama. The patient, a 4 year old girl, presented with fever, anemia, cervical lymphadenitis, hepatomegaly, lymphocytosis and histophagocytosis of red cells, lymphocytes, neutrophils and platelets. Spontaneous remission of the fever occurred sixty days after the onset of the disease. Although it was not possible to demonstrate serologically that the syndrome was due to acute toxoplasmosis, she was treated with sulfadiazine and pyrimethamine for fifteen days, on the 37th hospital day, and with clindamycin for ten days, consecutively. Remission occurred seventy days after the onset of fever. A second serological examination for toxoplasmosis (immunofluorescent antibodies) was positive in a titer of 1:2048 again, nine months after the first serology.
作者介绍了在巴拿马诊断出的首例良性噬血细胞综合征的临床病史。该患者为一名4岁女童，出现发热、贫血、颈部淋巴结炎、肝肿大、淋巴细胞增多以及红细胞、淋巴细胞、中性粒细胞和血小板的组织细胞吞噬现象。疾病发作60天后发热自行缓解。尽管血清学检查无法证明该综合征是由急性弓形虫病引起的，但在住院第37天时，她接受了磺胺嘧啶和乙胺嘧啶治疗15天，随后连续接受克林霉素治疗10天。发热70天后病情缓解。首次血清学检查9个月后，第二次弓形虫病血清学检查（免疫荧光抗体）再次呈阳性，滴度为1:2048。
