MIA：非靶向质量同位素组分析。
MIA: non-targeted mass isotopolome analysis.
作者信息
Weindl Daniel, Wegner Andre, Hiller Karsten
机构信息
Luxembourg Centre for Systems Biomedicine, University of Luxembourg, L-4362 Esch-sur-Alzette, Luxembourg.
出版信息
Bioinformatics. 2016 Sep 15;32(18):2875-6. doi: 10.1093/bioinformatics/btw317. Epub 2016 Jun 6.
UNLABELLED
MIA detects and visualizes isotopic enrichment in gas chromatography electron ionization mass spectrometry (GC-EI-MS) datasets in a non-targeted manner. It provides an easy-to-use graphical user interface that allows for visual mass isotopomer distribution analysis across multiple datasets. MIA helps to reveal changes in metabolic fluxes, visualizes metabolic proximity of isotopically enriched compounds and shows the fate of the applied stable isotope labeled tracer.
AVAILABILITY AND IMPLEMENTATION
Linux and Windows binaries, documentation, and sample data are freely available for download at http://massisotopolomeanalyzer.lu MIA is a stand-alone application implemented in C ++ and based on Qt5, NTFD and the MetaboliteDetector framework.
CONTACT
未标注
MIA以非靶向方式检测并可视化气相色谱电子电离质谱（GC-EI-MS）数据集中的同位素富集情况。它提供了一个易于使用的图形用户界面，可对多个数据集进行可视化的质量同位素异构体分布分析。MIA有助于揭示代谢通量的变化，可视化同位素富集化合物的代谢邻近性，并显示所应用的稳定同位素标记示踪剂的去向。
可用性与实现方式
Linux和Windows二进制文件、文档及示例数据可从http://massisotopolomeanalyzer.lu免费下载。MIA是一个用C++编写的独立应用程序，基于Qt5、NTFD和代谢物检测器框架。
联系方式
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