Lang Xiabing, Yang Yi, Chen Jianghua
Kidney Disease Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China.
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2016 Mar;45(2):208-13. doi: 10.3785/j.issn.1008-9292.2016.03.15.
Acute kidney injury (AKI) is a disease spectrum ranging from minimal elevation of serum creatinine to complete renal failure. It is significantly associated with increased mortality, length of hospital stay and medical care cost. With the increasing awareness of the importance of AKI, several high quality and multicenter epidemiological studies have been published recently in China. However, the results differ a lot due to the differences in regional economic development, the selection of target population and testing indicators, the disease definition and study strategies. The reported incidence of AKI in China is much lower than that in the developed countries. This article will analyze the current status and the problems facing AKI epidemiological studies of hospitalized patients with our own data and those from literature. The article intends to clarify the burden of AKI,to increase the awareness of AKI among clinicians and policy makers for achieving the goal of "zero by 2025" in China.
急性肾损伤（AKI）是一种疾病谱，范围从血清肌酐的轻微升高到完全肾衰竭。它与死亡率增加、住院时间延长和医疗费用显著相关。随着对AKI重要性的认识不断提高，中国最近发表了几项高质量的多中心流行病学研究。然而，由于区域经济发展、目标人群和检测指标的选择、疾病定义和研究策略的差异，结果差异很大。中国报道的AKI发病率远低于发达国家。本文将利用我们自己的数据以及文献中的数据，分析住院患者AKI流行病学研究的现状和面临的问题。本文旨在阐明AKI的负担，提高临床医生和政策制定者对AKI的认识，以实现中国“2025年零发病”的目标。
