Galeotti Jonathan, Sporn Thomas A, Ingram Peter, Wahidi Momen M, Roggli Victor L
a Department of Pathology , Duke University Medical Center , Durham , NC , USA.
b Department of Medicine , Duke University Medical Center , Durham , NC , USA.
Ultrastruct Pathol. 2016 May-Jun;40(3):159-62. doi: 10.3109/01913123.2016.1170084.
Pneumoconiosis is often considered a disease of the lung initiated by exposure to dust or other airborne particles, resulting in injury to the lungs. The term "endogenous pneumoconiosis" has been used in the literature to describe the deposition of compounds on the elastic fibers of the lung, usually in the setting of cardiac failure. In the case we present here, the patient aspirated a foreign body resulting in damage to the lung tissue and subsequent deposition of endogenous compounds on the elastic fibers of the pulmonary parenchyma and vasculature. We determined the composition of this mineral and mapped the distribution of elements using a combination of backscattered electron microscopy and energy dispersive spectrometry.
尘肺病通常被认为是一种因接触灰尘或其他空气传播颗粒而引发的肺部疾病，会导致肺部损伤。文献中使用“内源性尘肺病”一词来描述化合物在肺弹性纤维上的沉积，通常发生在心力衰竭的情况下。在我们这里呈现的病例中，患者吸入异物导致肺组织受损，随后内源性化合物沉积在肺实质和脉管系统的弹性纤维上。我们使用背散射电子显微镜和能量色散光谱相结合的方法确定了这种矿物质的成分并绘制了元素分布图。
