Tustumi Francisco, Takeda Flavio Roberto, Kimura Cintia Mayumi Sakurai, Sallum Rubens Antônio Aissar, Ribeiro Ulysses, Cecconello Ivan
Departamento de Cirurgia do Aparelho Digestivo do Hospital das Clínicas de São Paulo; Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brasil. , Universidade de São Paulo, Hospital das Clínicas de São Paulo, Faculdade de Medicina, Universidade de São Paulo, São Paulo SP , Brazil.
Arq Gastroenterol. 2016 Jan-Mar;53(1):44-8. doi: 10.1590/S0004-28032016000100009.
Esophageal cancer is one of the leading causes of mortality among the neoplasms that affect the gastrointestinal tract. There are several factors that contribute for development of an epidemiological esophageal cancer profile in a population.
This study aims to describe both clinically and epidemiologically the population of patients with diagnosis of esophageal cancer treated in a quaternary attention institute for cancer from January, 2009 to December, 2011, in Sao Paulo, Brazil.
The charts of all patients diagnosed with esophageal cancer from January, 2009, to December, 2011, in a Sao Paulo (Brazil) quaternary oncology institute were retrospectively reviewed.
Squamous cell cancer made up to 80% of the cases of esophageal cancer. Average age at diagnosis was 60.66 years old for esophageal adenocarcinoma and 62 for squamous cell cancer, average time from the beginning of symptoms to the diagnosis was 3.52 months for esophageal adenocarcinoma and 4.2 months for squamous cell cancer. Average time for initiating treatment when esophageal cancer is diagnosed was 4 months for esophageal adenocarcinoma and 4.42 months for squamous cell cancer. There was a clear association between squamous cell cancer and head and neck cancers, as well as certain habits, such as smoking and alcoholism, while adenocarcinoma cancer showed more association with gastric cancer and gastroesophageal reflux disease. Tumoral bleeding and pneumonia were the main causes of death. No difference in survival rate was noted between the two groups.
Adenocarcinoma and squamous cell carcinoma are different diseases, but both are diagnosed in advanced stages in Brazil, compromising the patients' possibilities of cure.
食管癌是影响胃肠道的肿瘤中导致死亡的主要原因之一。有几个因素促成了人群中食管癌流行病学特征的形成。
本研究旨在从临床和流行病学角度描述2009年1月至2011年12月在巴西圣保罗一家癌症四级诊疗机构接受治疗的食管癌确诊患者群体。
回顾性分析了巴西圣保罗一家癌症四级诊疗机构2009年1月至2011年12月期间所有确诊食管癌患者的病历。
鳞状细胞癌占食管癌病例的80%。食管腺癌确诊时的平均年龄为60.66岁，鳞状细胞癌为62岁；食管腺癌从症状出现到确诊的平均时间为3.52个月，鳞状细胞癌为4.2个月。食管癌确诊后开始治疗的平均时间，食管腺癌为4个月，鳞状细胞癌为4.42个月。鳞状细胞癌与头颈癌以及某些习惯（如吸烟和酗酒）之间存在明显关联，而腺癌与胃癌和胃食管反流病的关联更为密切。肿瘤出血和肺炎是主要死因。两组的生存率无差异。
腺癌和鳞状细胞癌是不同的疾病，但在巴西均在晚期被诊断出来，这影响了患者的治愈可能性。
