Rocha-Filho Duilio R, Peixoto Renata D'Alpino, Weschenfelder Rui F, Rego Juliana F M, Riechelmann Rachel, Coutinho Anelisa K, Fernandes Gustavo S, Jacome Alexandre A, Andrade Aline C, Murad Andre M, Mello Celso A L, Miguel Diego S C G, Gomes Diogo B D, Racy Douglas J, Moraes Eduardo D, Akaishi Eduardo H, Carvalho Elisangela S, Mello Evandro S, Filho Fauze Maluf, Coimbra Felipe J F, Capareli Fernanda C, Arruda Fernando F, Vieira Fernando M A C, Takeda Flavio R, Cotti Guilherme C C, Pereira Guilherme L S, Paulo Gustavo A, Ribeiro Héber S C, Lourenco Laercio G, Crosara Marcela, Toneto Marcelo G, Oliveira Marcos B, de Lourdes Oliveira Maria, Begnami Maria Dirlei, Forones Nora M, Yagi Osmar, Ashton-Prolla Patricia, Aguillar Patricia B, Amaral Paulo C G, Hoff Paulo M, Araujo Raphael L C, Di Paula Filho Raphael P, Gansl Rene C, Gil Roberto A, Pfiffer Tulio E F, Souza Tulio, Ribeiro Ulysses, Jesus Victor Hugo F, Costa Wilson L, Prolla Gabriel
Hospital Universitário Walter Cantídio, 60430-372 Fortaleza, Brazil.
Grupo Oncologia D'Or, 04535-110 São Paulo, Brazil.
Ecancermedicalscience. 2021 Mar 2;15:1195. doi: 10.3332/ecancer.2021.1195. eCollection 2021.
Oesophageal cancer is among the ten most common types of cancer worldwide. More than 80% of the cases and deaths related to the disease occur in developing countries. Local socio-economic, epidemiologic and healthcare particularities led us to create a Brazilian guideline for the management of oesophageal and oesophagogastric junction (OGJ) carcinomas. The Brazilian Group of Gastrointestinal Tumours invited 50 physicians with different backgrounds, including radiology, pathology, endoscopy, nuclear medicine, genetics, oncological surgery, radiotherapy and clinical oncology, to collaborate. This document was prepared based on an extensive review of topics related to heredity, diagnosis, staging, pathology, endoscopy, surgery, radiation, systemic therapy (including checkpoint inhibitors) and follow-up, which was followed by presentation, discussion and voting by the panel members. It provides updated evidence-based recommendations to guide clinical management of oesophageal and OGJ carcinomas in several scenarios and clinical settings.
食管癌是全球十大最常见的癌症类型之一。超过80%的与该疾病相关的病例和死亡发生在发展中国家。当地的社会经济、流行病学和医疗保健特点促使我们制定了巴西食管癌和食管胃交界(OGJ)癌管理指南。巴西胃肠肿瘤小组邀请了50名背景各异的医生合作,这些医生包括放射学、病理学、内窥镜检查、核医学、遗传学、肿瘤外科、放射治疗和临床肿瘤学领域的专家。本文件基于对与遗传、诊断、分期、病理学、内窥镜检查、手术、放疗、全身治疗(包括检查点抑制剂)和随访等相关主题的广泛综述编写而成,随后由小组成员进行陈述、讨论和投票。它提供了基于最新证据的建议,以指导在多种情况和临床环境下对食管癌和OGJ癌的临床管理。