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吸入烟雾会增加小儿烧伤患者对重症监护的需求以及发病率。

Smoke inhalation increases intensive care requirements and morbidity in paediatric burns.

作者信息

Tan Alethea, Smailes Sarah, Friebel Thessa, Magdum Ashish, Frew Quentin, El-Muttardi Naguib, Dziewulski Peter

机构信息

St Andrew Burns Intensive Unit, Broomfield Hospital, Court Road, Chelmsford, CM1 7ET, United Kingdom; St Andrew Anglia Ruskin Research Unit, Faculty of Medical Sciences, 1-2 Bishop Hall Lane, CM11SQ, United Kingdom.

St Andrew Burns Intensive Unit, Broomfield Hospital, Court Road, Chelmsford, CM1 7ET, United Kingdom.

出版信息

Burns. 2016 Aug;42(5):1111-1115. doi: 10.1016/j.burns.2016.02.010. Epub 2016 Jun 6.

Abstract

Burn survival has improved with advancements in fluid resuscitation, surgical wound management, wound dressings, access to antibiotics and nutritional support for burn patients. Despite these advancements, the presence of smoke inhalation injury in addition to a cutaneous burn still significantly increases morbidity and mortality. The pathophysiology of smoke inhalation has been well studied in animal models. Translation of this knowledge into effectiveness of clinical management and correlation with patient outcomes including the paediatric population, is still limited. We retrospectively reviewed our experience of 13 years of paediatric burns admitted to a regional burn's intensive care unit. We compared critical care requirements and patient outcomes between those with cutaneous burns only and those with concurrent smoke inhalation injury. Smoke inhalation increases critical care requirements and mortality in the paediatric burn population. Therefore, early critical care input in the management of these patients is advised.

摘要

随着液体复苏、手术伤口管理、伤口敷料、烧伤患者抗生素使用及营养支持等方面的进展,烧伤患者的存活率有所提高。尽管有这些进展,但除皮肤烧伤外伴有吸入性损伤仍会显著增加发病率和死亡率。吸入烟雾的病理生理学在动物模型中已得到充分研究。将这些知识转化为临床管理的有效性以及与包括儿科患者在内的患者预后的相关性仍然有限。我们回顾性分析了一家地区烧伤重症监护病房收治的13年儿科烧伤病例。我们比较了仅皮肤烧伤患者和同时伴有吸入性损伤患者的重症监护需求和患者预后。吸入性损伤增加了儿科烧伤患者的重症监护需求和死亡率。因此,建议在这些患者的管理中尽早进行重症监护干预。

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