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用于肥厚性瘢痕和瘢痕疙瘩体积测量的三维成像,一种先前经验证的简化技术在临床环境中的可靠性。

Three-dimensional imaging for volume measurement of hypertrophic and keloid scars, reliability of a previously validated simplified technique in clinical setting.

作者信息

Verhiel S H W L, Piatkowski de Grzymala A A, Van den Kerckhove E, Colla C, van der Hulst R R W J

机构信息

Plastic Surgery, Maastricht University Medical Center, Maastricht, Limburg, The Netherlands.

Department of Rehabilitation Sciences, KU Leuven, Heverlee, Belgium.

出版信息

Skin Res Technol. 2016 Nov;22(4):513-518. doi: 10.1111/srt.12296. Epub 2016 Jun 10.

Abstract

INTRODUCTION

Evidence behind many of the current treatments in hypertrophic and keloid scars remains limited. Current objective methods to assess efficacy and provide follow-up can be complex and are not easily applied in clinical setting. The aim of this study was to assess reliability of a recently validated simplified technique for volume measurement in clinical practice.

METHODS

Volume measurement of 28 hypertrophic and keloid scars was conducted in 22 consecutive patients, using a three-dimensional stereophotogrammetry. Intra- and inter-rater reliability was assessed by the intraclass correlation coefficient (ICC) and the coefficient of variation (CV). The measurement error was expressed as limits of agreement (LoA).

RESULTS

The simplified method for three-dimensional volume measurement showed good intra-rater reliability with an ICC of 0.997 and a CV of 7.3%, and a good inter-rater reliability with an ICC of 0.999 and a CV of 5.7%. The plot of the differences and LoA showed near-perfect agreement between observers.

CONCLUSION

Objective evaluation of scar volume using the simplified three-dimensional measurement technique may complement subjective scoring and improve the ability to quantitatively compare the response to therapeutic methods.

摘要

引言

目前许多用于治疗增生性瘢痕和瘢痕疙瘩的方法背后的证据仍然有限。当前评估疗效和进行随访的客观方法可能很复杂,且不易应用于临床环境。本研究的目的是评估一种最近验证的简化技术在临床实践中进行体积测量的可靠性。

方法

对22例连续患者的28个增生性瘢痕和瘢痕疙瘩进行体积测量,采用三维立体摄影测量法。通过组内相关系数(ICC)和变异系数(CV)评估评分者内和评分者间的可靠性。测量误差以一致性界限(LoA)表示。

结果

三维体积测量的简化方法显示出良好的评分者内可靠性,ICC为0.997,CV为7.3%,以及良好的评分者间可靠性,ICC为0.999,CV为5.7%。差异图和LoA显示观察者之间几乎完全一致。

结论

使用简化的三维测量技术对瘢痕体积进行客观评估,可能补充主观评分,并提高定量比较治疗方法反应的能力。

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