Li Long, Wu Yuan, Hu Liu, Xu Hongbin, He Haicui, Hu Desheng
Department of Radiation Oncology, Hubei Cancer Hospital, Wuhan, Hubei 430079, P.R. China.
Mol Clin Oncol. 2016 Jun;4(6):1039-1040. doi: 10.3892/mco.2016.852. Epub 2016 Apr 7.
Nerve root metastasis of cancer has been rarely reported. We herein report the case of a cervical cancer patient with metastasis to peripheral nerve roots. A 47 year-old woman with cervical squamous cell carcinoma was admitted to our department with a 6-month history of right leg pain, and was investigated for cancer recurrence. Magnetic resonance imaging revealed lymph node metastasis near the right iliac blood vessels; the patient was then treated with chemotherapy with paclitaxel and carboplatin. However, the pain worsened and the muscle strength of her right leg decreased. On positron emission tomography/computed tomography scans, the sacral plexus L5/S1 and L4/5 nerves appeared thickened, suggesting nerve metastases. Intensity-modulated radiation therapy was applied, with notable clinical benefit. However, the patient succumbed to the disease 3 months later.
癌症神经根转移鲜有报道。我们在此报告一例宫颈癌患者发生外周神经根转移的病例。一名47岁的宫颈鳞状细胞癌女性因右腿疼痛6个月入住我科,接受癌症复发检查。磁共振成像显示右髂血管附近有淋巴结转移;随后患者接受了紫杉醇和卡铂化疗。然而,疼痛加剧,右腿肌力下降。在正电子发射断层扫描/计算机断层扫描中,骶丛L5/S1和L4/5神经增粗,提示神经转移。应用了调强放射治疗,临床效果显著。然而,患者3个月后死于该疾病。