Hsieh Scott S, Peng Mark V, May Christopher A, Shunhavanich Picha, Fleischmann Dominik, Pelc Norbert J
Departments of Radiology, Stanford University, Stanford, CA 94305, USA. Departments of Electrical Engineering, Stanford University, Stanford, CA 94305, USA.
Phys Med Biol. 2016 Jul 7;61(13):4974-88. doi: 10.1088/0031-9155/61/13/4974. Epub 2016 Jun 10.
The piecewise-linear dynamic attenuator has been proposed as a mechanism in CT scanning for personalizing the x-ray illumination on a patient- and application-specific basis. Previous simulations have shown benefits in image quality, scatter, and dose objectives. We report on the first prototype implementation. This prototype is reduced in scale and speed and is integrated into a tabletop CT system with a smaller field of view (25 cm) and longer scan time (42 s) compared to a clinical system. Stainless steel wedges were machined and affixed to linear actuators, which were in turn held secure by a frame built using rapid prototyping technologies. The actuators were computer-controlled, with characteristic noise of about 100 microns. Simulations suggest that in a clinical setting, the impact of actuator noise could lead to artifacts of only 1 HU. Ring artifacts were minimized by careful design of the wedges. A water beam hardening correction was applied and the scan was collimated to reduce scatter. We scanned a 16 cm water cylinder phantom as well as an anthropomorphic pediatric phantom. The artifacts present in reconstructed images are comparable to artifacts normally seen with this tabletop system. Compared to a flat-field reference scan, increased detectability at reduced dose is shown and streaking is reduced. Artifacts are modest in our images and further refinement is possible. Issues of mechanical speed and stability in the challenging clinical CT environment will be addressed in a future design.
分段线性动态衰减器已被提议作为CT扫描中的一种机制,用于根据患者和应用的具体情况对X射线照射进行个性化设置。先前的模拟已显示出在图像质量、散射和剂量目标方面的优势。我们报告了首个原型实现情况。该原型在规模和速度上有所缩减,并集成到了一个桌面CT系统中,与临床系统相比,其视野较小(25厘米)且扫描时间较长(42秒)。不锈钢楔形块经过加工并固定到线性致动器上,而线性致动器又通过使用快速成型技术构建的框架固定牢固。致动器由计算机控制,特征噪声约为100微米。模拟表明,在临床环境中,致动器噪声的影响可能仅导致1HU的伪影。通过精心设计楔形块,环形伪影被最小化。应用了水束硬化校正,并对扫描进行准直以减少散射。我们扫描了一个16厘米的水模体以及一个拟人化儿科模体。重建图像中出现的伪影与该桌面系统通常看到的伪影相当。与平场参考扫描相比,在降低剂量的情况下显示出更高的可检测性,并且条纹减少。我们图像中的伪影较小,进一步改进是可能的。在未来的设计中将解决具有挑战性的临床CT环境中的机械速度和稳定性问题。