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基于X射线CT部分角度重建图像的心脏运动校正

Cardiac motion correction based on partial angle reconstructed images in x-ray CT.

作者信息

Kim Seungeon, Chang Yongjin, Ra Jong Beom

机构信息

Department of Electrical Engineering, KAIST, Daejeon 305-701, Republic of Korea.

出版信息

Med Phys. 2015 May;42(5):2560-71. doi: 10.1118/1.4918580.

Abstract

PURPOSE

Cardiac x-ray CT imaging is still challenging due to heart motion, which cannot be ignored even with the current rotation speed of the equipment. In response, many algorithms have been developed to compensate remaining motion artifacts by estimating the motion using projection data or reconstructed images. In these algorithms, accurate motion estimation is critical to the compensated image quality. In addition, since the scan range is directly related to the radiation dose, it is preferable to minimize the scan range in motion estimation. In this paper, the authors propose a novel motion estimation and compensation algorithm using a sinogram with a rotation angle of less than 360°. The algorithm estimates the motion of the whole heart area using two opposite 3D partial angle reconstructed (PAR) images and compensates the motion in the reconstruction process.

METHODS

A CT system scans the thoracic area including the heart over an angular range of 180° + α + β, where α and β denote the detector fan angle and an additional partial angle, respectively. The obtained cone-beam projection data are converted into cone-parallel geometry via row-wise fan-to-parallel rebinning. Two conjugate 3D PAR images, whose center projection angles are separated by 180°, are then reconstructed with an angular range of β, which is considerably smaller than a short scan range of 180° + α. Although these images include limited view angle artifacts that disturb accurate motion estimation, they have considerably better temporal resolution than a short scan image. Hence, after preprocessing these artifacts, the authors estimate a motion model during a half rotation for a whole field of view via nonrigid registration between the images. Finally, motion-compensated image reconstruction is performed at a target phase by incorporating the estimated motion model. The target phase is selected as that corresponding to a view angle that is orthogonal to the center view angles of two conjugate PAR images. To evaluate the proposed algorithm, digital XCAT and physical dynamic cardiac phantom datasets are used. The XCAT phantom datasets were generated with heart rates of 70 and 100 bpm, respectively, by assuming a system rotation time of 300 ms. A physical dynamic cardiac phantom was scanned using a slowly rotating XCT system so that the effective heart rate will be 70 bpm for a system rotation speed of 300 ms.

RESULTS

In the XCAT phantom experiment, motion-compensated 3D images obtained from the proposed algorithm show coronary arteries with fewer motion artifacts for all phases. Moreover, object boundaries contaminated by motion are well restored. Even though object positions and boundary shapes are still somewhat different from the ground truth in some cases, the authors see that visibilities of coronary arteries are improved noticeably and motion artifacts are reduced considerably. The physical phantom study also shows that the visual quality of motion-compensated images is greatly improved.

CONCLUSIONS

The authors propose a novel PAR image-based cardiac motion estimation and compensation algorithm. The algorithm requires an angular scan range of less than 360°. The excellent performance of the proposed algorithm is illustrated by using digital XCAT and physical dynamic cardiac phantom datasets.

摘要

目的

心脏X射线CT成像由于心脏运动仍然具有挑战性,即使在设备当前的旋转速度下,心脏运动也不容忽视。为此,人们开发了许多算法,通过使用投影数据或重建图像估计运动来补偿剩余的运动伪影。在这些算法中,精确的运动估计对于补偿后的图像质量至关重要。此外,由于扫描范围与辐射剂量直接相关,因此在运动估计中最好尽量减小扫描范围。在本文中,作者提出了一种使用旋转角度小于360°的正弦图的新型运动估计和补偿算法。该算法使用两个相对的3D部分角度重建(PAR)图像估计整个心脏区域的运动,并在重建过程中补偿运动。

方法

CT系统在180°+α+β的角度范围内扫描包括心脏的胸部区域,其中α和β分别表示探测器扇形角和附加的部分角度。通过逐行扇形到平行重排将获得的锥束投影数据转换为锥平行几何形状。然后使用β的角度范围重建两个共轭3D PAR图像,其中心投影角度相差180°,该角度范围比180°+α的短扫描范围小得多。尽管这些图像包含干扰精确运动估计的有限视角伪影,但它们具有比短扫描图像更好的时间分辨率。因此,在对这些伪影进行预处理后,作者通过图像之间的非刚性配准估计全视野半旋转期间的运动模型。最后,通过合并估计的运动模型在目标相位进行运动补偿图像重建。目标相位被选择为与两个共轭PAR图像的中心视角正交的视角对应的相位。为了评估所提出的算法,使用了数字XCAT和物理动态心脏体模数据集。通过假设系统旋转时间为300 ms,分别以70和100 bpm的心率生成XCAT体模数据集。使用缓慢旋转的XCT系统扫描物理动态心脏体模,以便对于300 ms的系统旋转速度,有效心率为70 bpm。

结果

在XCAT体模实验中,从所提出的算法获得的运动补偿3D图像在所有相位都显示出冠状动脉的运动伪影较少。此外,被运动污染的物体边界得到了很好的恢复。尽管在某些情况下物体位置和边界形状仍与真实情况有些不同,但作者发现冠状动脉的可见性明显改善,运动伪影大大减少。物理体模研究还表明,运动补偿图像的视觉质量有了很大提高。

结论

作者提出了一种基于PAR图像的新型心脏运动估计和补偿算法。该算法需要小于360°的角扫描范围。通过使用数字XCAT和物理动态心脏体模数据集说明了所提出算法的优异性能。

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