Temin P A, Zavadenko N N, Kamennykh L N, Nikanorova M Iu
Zh Nevropatol Psikhiatr Im S S Korsakova. 1989;89(3):93-6.
A total of 70 patients with Duchenne progressive muscular dystrophy (DPMD) aged 3 to 20 were enrolled in this study. Peculiarities of the diagnosis and diagnostic errors were shown at different stages of medical follow-up of the patients. A half of the patients had pediatrists and orthopedists as their first doctors. Upon the initial investigation, DPMD was diagnosed in about 1/3 of the patients. Retarded motor and psycholingual development were the first signs of the disease in 72.9% and 37.1% of the cases, respectively. Bones and cartilages were also frequently changed. To improve the early DPMD diagnosis it is essential that pediatrists child surgeons and ortopedists be largely informed about the clinical features of the disease.
本研究共纳入70例年龄在3至20岁的杜氏进行性肌营养不良（DPMD）患者。研究显示了患者医疗随访不同阶段的诊断特点及诊断错误情况。一半患者首诊医生为儿科医生和骨科医生。初步检查时，约1/3的患者被诊断为DPMD。运动发育迟缓及精神语言发育迟缓分别是72.9%和37.1%病例的首发症状。骨骼和软骨也常有改变。为改善DPMD的早期诊断，儿科医生、儿童外科医生和骨科医生必须充分了解该疾病的临床特征。
