Golabek Tomasz, Skalski Michal, Przydacz Mikolaj, Świerkosz Agata, Siwek Marcin, Golabek Katarzyna, Stangel-Wojcikiewicz Klaudia, Dudek Dominika, Chlosta Piotr
Klinika Urologii UJ CM.
Klinika Psychiatrii Dorosłych Szpitala Uniwersyteckiego w Krakowie.
Psychiatr Pol. 2016;50(2):417-30. doi: 10.12740/PP/OnlineFirst/59162.
Lower urinary tract symptoms (LUTS) remain highly prevalent worldwide, and are well known to negatively impact patients' quality of life, sleep and psychosocial wellbeing. Conversely, both depression and anxiety have been shown to have a negative effect on perception, development and prolongation of LUTS. This paper provides an overview of an association between the lower urinary tract symptoms, depression and anxiety. It also explores possible common mechanisms underlying the causes of both conditions. There has been a large body of evidence linking LUTS with anxiety and/or depression. Studies have documented not only a significant impact of LUTS on the psychosocial wellbeing, but also showed a strong negative effect of depression and anxiety on perception, development and prolongation of LUTS. High level of psychiatric morbidity has important implications on the appropriate management in patients with LUTS, as well as LUTS may have important implications on development and management of depression and anxiety. Therefore, clinicians should be aware of the bidirectional association between LUTS and anxiety and/or depression, as some patients may require a multidisciplinary approach and a combined treatment. The precise common mechanism underlying LUTS, depression and anxiety remain largely unknown and further research is needed to elucidate the underlying pathophysiological pathways.
下尿路症状（LUTS）在全球范围内仍然非常普遍，众所周知，它会对患者的生活质量、睡眠和心理社会幸福感产生负面影响。相反，抑郁和焦虑都已被证明会对LUTS的感知、发展和持续时间产生负面影响。本文概述了下尿路症状、抑郁和焦虑之间的关联。它还探讨了这两种情况病因背后可能的共同机制。有大量证据将LUTS与焦虑和/或抑郁联系起来。研究不仅记录了LUTS对心理社会幸福感的重大影响，还表明抑郁和焦虑对LUTS的感知、发展和持续时间有强烈的负面影响。高精神疾病发病率对LUTS患者的适当管理具有重要意义，同样，LUTS可能对抑郁和焦虑的发展及管理也具有重要意义。因此，临床医生应意识到LUTS与焦虑和/或抑郁之间的双向关联，因为一些患者可能需要多学科方法和联合治疗。LUTS、抑郁和焦虑背后的确切共同机制在很大程度上仍然未知，需要进一步研究以阐明潜在的病理生理途径。
