Przydacz Mikolaj, Rajwa Pawel, De Cillis Sabrina, Guillot-Tantay Cyrille, Herve Francois, Tienza Antonio, Tutolo Manuela, Gokhan Culha Mehmet, Geretto Paolo, Raison Nicholas, Werneburg Glenn T, Miszczyk Marcin, Gomez Rivas Juan, Phe Veronique, Chlosta Piotr, Osman Nadir
Department of Urology, Jagiellonian University Medical College, Krakow, Poland.
Department of Urology, Medical University of Silesia, Zabrze, Poland.
Eur Urol Open Sci. 2024 Sep 11;68:61-67. doi: 10.1016/j.euros.2024.08.009. eCollection 2024 Oct.
Lower urinary tract symptoms (LUTS) and overactive bladder (OAB) intimately affect the psychological wellbeing and mental health of men. However, to date, the association of aggression with LUTS and OAB has not been investigated. To address this knowledge gap, we evaluated the association of aggression with LUTS and OAB in a large representative cohort of men at the population level.
We used computer-assisted web interviews that included reliable questionnaires for assessment of LUTS, OAB, and aggression. A population-representative group of men was based on the most recent census. For data analysis, we developed univariate and multivariate regression models.
We analyzed data for a cohort of 3001 men that was representative for age and place of residence. Aggression was more prevalent among respondents with LUTS and OAB in comparison to men without these conditions ( < 0.001). The scores for aggression were directly proportional to the scores for LUTS and OAB (Spearman's rank correlation coefficients of 0.261 for LUTS and 0.284 for OAB). Univariate linear regression models revealed an association between aggression and LUTS or OAB in all age groups. Finally, multivariable linear regression models confirmed that correlations of aggression with LUTS and OAB were independent of age, sociodemographic parameters, comorbidities, and lifestyle habits (regression coefficients of 0.013 for LUTS and 0.024 for OAB).
Our study is the first to show that aggression among men is consistently associated with LUTS and OAB. Our results open a new research area on the effect of LUTS and OAB or their causes on psychological wellbeing and mental health, and may even support screening for hostile behavior in the clinical setting for individuals who report LUTS and OAB.
We performed the first study to investigate whether aggression is linked to lower urinary tract symptoms (LUTS) and overactive bladder (OAB). Results from our survey in a representative group of men in Poland show that aggression is linked to LUTS and OAB. More research is needed to confirm these results.
下尿路症状（LUTS）和膀胱过度活动症（OAB）对男性的心理健康有着密切影响。然而，迄今为止，攻击行为与LUTS和OAB之间的关联尚未得到研究。为填补这一知识空白，我们在一个具有广泛代表性的男性队列中，从人群层面评估了攻击行为与LUTS和OAB之间的关联。
我们采用计算机辅助网络访谈，其中包括用于评估LUTS、OAB和攻击行为的可靠问卷。以最新的人口普查为基础选取具有人群代表性的男性群体。在数据分析方面，我们构建了单变量和多变量回归模型。
我们分析了一个由3001名男性组成的队列数据，该队列在年龄和居住地点方面具有代表性。与没有这些症状的男性相比，有LUTS和OAB的受访者中攻击行为更为普遍（<0.001）。攻击行为得分与LUTS和OAB得分成正比（LUTS的斯皮尔曼等级相关系数为0.261，OAB为0.284）。单变量线性回归模型显示，在所有年龄组中，攻击行为与LUTS或OAB之间均存在关联。最后，多变量线性回归模型证实，攻击行为与LUTS和OAB的相关性独立于年龄、社会人口学参数、合并症和生活方式习惯（LUTS的回归系数为0.013，OAB为0.024）。
我们的研究首次表明，男性中的攻击行为与LUTS和OAB始终存在关联。我们的结果开启了一个关于LUTS和OAB及其病因对心理健康影响的新研究领域，甚至可能支持在临床环境中对报告有LUTS和OAB的个体进行攻击性行为筛查。
我们进行了第一项研究，以调查攻击行为是否与下尿路症状（LUTS）和膀胱过度活动症（OAB）有关。我们在波兰一组具有代表性男性中的调查结果显示，攻击行为与LUTS和OAB有关。需要更多研究来证实这些结果。
