Department of Biology, Ecology and Earth Sciences, University of Calabria, 87036, Arcavacata di Rende, CS, Italy.
Department of Biology, Ecology and Earth Sciences, University of Calabria, 87036, Arcavacata di Rende, CS, Italy.
Environ Pollut. 2016 Sep;216:314-323. doi: 10.1016/j.envpol.2016.06.007. Epub 2016 Jun 9.
Both occupational and environmental exposure to asbestos-mineral fibres can be associated with lung diseases. The pathogenic effects are related to the dimension, biopersistence and chemical composition of the fibres. In addition to the major mineral elements, mineral fibres contain trace elements and their content may play a role in fibre toxicity. To shed light on the role of trace elements in asbestos carcinogenesis, knowledge on their concentration in asbestos-mineral fibres is mandatory. It is possible that trace elements play a synergetic factor in the pathogenesis of diseases caused by the inhalation of mineral fibres. In this paper, the concentration levels of trace elements from three chrysotile samples, four amphibole asbestos samples (UICC amosite, UICC anthophyllite, UICC crocidolite and tremolite) and fibrous erionite from Jersey, Nevada (USA) were determined using inductively coupled plasma mass spectrometry (ICP-MS). For all samples, the following trace elements were measured: Li, Be, Sc, V, Cr, Mn, Co, Ni, Cu, Zn, As, Rb, Sr, Y, Sb, Cs, Ba, La, Pb, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, Th, U. Their distribution in the various mineral species is thoroughly discussed. The obtained results indicate that the amount of trace metals such as Mn, Cr, Co, Ni, Cu and Zn is higher in anthophyllite and chrysotile samples, whereas the amount of rare earth elements (REE) is higher in erionite and tremolite samples. The results of this work can be useful to the pathologists and biochemists who use asbestos minerals and fibrous erionite in-vitro studies as positive cyto- and geno-toxic standard references.
职业和环境暴露于石棉矿物纤维都可能与肺部疾病有关。致病作用与纤维的尺寸、生物持久性和化学成分有关。除了主要的矿物质元素外，矿物纤维还含有微量元素，其含量可能在纤维毒性中起作用。为了阐明微量元素在石棉致癌中的作用，必须了解石棉矿物纤维中微量元素的浓度。微量元素可能在吸入矿物纤维引起的疾病的发病机制中起协同作用。在本文中，使用电感耦合等离子体质谱法（ICP-MS）测定了来自三个温石棉样品、四个角闪石石棉样品（UICC 温石棉、UICC 铁石棉、UICC 青石棉和透闪石）和来自内华达州泽西岛的纤维状直闪石的微量元素浓度。对于所有样品，测量了以下微量元素：Li、Be、Sc、V、Cr、Mn、Co、Ni、Cu、Zn、As、Rb、Sr、Y、Sb、Cs、Ba、La、Pb、Ce、Pr、Nd、Sm、Eu、Gd、Tb、Dy、Ho、Er、Tm、Yb、Lu、Th、U。详细讨论了它们在各种矿物物种中的分布。所得结果表明，在铁石棉和温石棉样品中，Mn、Cr、Co、Ni、Cu 和 Zn 等微量元素的含量较高，而在直闪石和透闪石样品中，稀土元素（REE）的含量较高。这项工作的结果可能对病理学家和生物化学家有用，他们将石棉矿物和纤维状直闪石用作体外研究的阳性细胞毒性和遗传毒性标准参考。
