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评估美国外科医师学会国家外科质量改进项目手术风险计算器在开放性腹疝修补术中的预测准确性。

Assessing the predictive accuracy of the American College of Surgeons National Surgical Quality Improvement Project Surgical Risk Calculator in open ventral hernia repair.

作者信息

Basta Marten N, Bauder Andrew R, Kovach Stephen J, Fischer John P

机构信息

Department of Plastic Surgery, Brown University and Rhode Island Hospital, Providence, RI, USA.

Division of Plastic Surgery, Perelman School of Medicine at the University of Pennsylvania, University of Pennsylvania Health System, Philadelphia, PA, USA.

出版信息

Am J Surg. 2016 Aug;212(2):272-81. doi: 10.1016/j.amjsurg.2016.01.034. Epub 2016 May 4.

Abstract

BACKGROUND

Preoperative surgical risk assessment continues to be a critical component of clinical decision-making. The ACS Universal Risk Calculator estimates risk for several outcomes based on individual risk profiles. Although this represents a tremendous step toward improving outcomes, studies have reported inaccuracies among certain patient populations. This study aimed to assess the predictive accuracy of the American College of Surgeons' (ACS) Risk Calculator in patients undergoing open ventral hernia repair (VHR).

METHODS

A review of patients undergoing open, isolated VHR between 7/1/2007 and 7/1/2014 by a single surgeon was performed. Risk factors and outcomes were collected as defined by National Surgical Quality Improvement Project. Thirty-day outcomes included serious complication, venous thromboembolism, medical morbidity, surgical site infection (SSI), unplanned reoperation, mortality, and length of stay (LOS). Patient profiles were entered into the ACS Surgical Risk Calculator and outcome-specific risk predictions recorded. Prediction accuracy was assessed using the Brier score and receiver-operator area under the curve (AUC).

RESULTS

One hundred forty-two patients undergoing open VHR were included. ACS predictions were accurate for cardiac complications (Brier = .02), venous thromboembolism (Brier = .08), reoperation (Brier = .10), and mortality (Brier = .01). Significantly, underestimated outcomes included SSI (Brier = .14), serious complication (Brier = .30), and any complication (Brier = .34). Discrimination ranged from highly accurate (mortality, AUC = .99) to indiscriminate (SSI, AUC = .57). Predicted LOS was 3-fold shorter than observed (2.4 vs 7.4 days, P <.001).

CONCLUSIONS

The ACS Surgical Risk Calculator accurately predicted medical complications, reoperation, and 30-day mortality. However, SSIs, serious complications, and LOS were significantly underestimated. These findings suggest that additional considerations are needed to better estimate complications after open VHR.

摘要

背景

术前手术风险评估仍然是临床决策的关键组成部分。美国外科医师学会通用风险计算器根据个体风险概况估算多种结局的风险。尽管这代表着在改善结局方面迈出了巨大一步,但研究报告称某些患者群体存在风险估算不准确的情况。本研究旨在评估美国外科医师学会(ACS)风险计算器在接受开放性腹疝修补术(VHR)患者中的预测准确性。

方法

对2007年7月1日至2014年7月1日期间由一名外科医生实施开放性单纯VHR的患者进行回顾性研究。按照国家外科质量改进项目的定义收集风险因素和结局。30天结局包括严重并发症、静脉血栓栓塞、内科疾病、手术部位感染(SSI)、计划外再次手术、死亡率和住院时间(LOS)。将患者资料录入ACS手术风险计算器并记录特定结局的风险预测值。使用Brier评分和曲线下受试者工作特征面积(AUC)评估预测准确性。

结果

纳入142例接受开放性VHR的患者。ACS对心脏并发症(Brier = 0.02)、静脉血栓栓塞(Brier = 0.08)、再次手术(Brier = 0.10)和死亡率(Brier = 0.01)的预测准确。值得注意的是,被低估的结局包括SSI(Brier = 0.14)、严重并发症(Brier = 0.30)和任何并发症(Brier = 0.34)。辨别能力从高度准确(死亡率,AUC = 0.99)到无区分能力(SSI,AUC = 0.57)不等。预测的LOS比观察值短3倍(2.4天对7.4天,P < 0.001)。

结论

ACS手术风险计算器准确预测了内科并发症、再次手术和30天死亡率。然而,SSI、严重并发症和LOS被显著低估。这些发现表明,需要更多因素来更好地估计开放性VHR后的并发症。

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