Alsomaili Mohammed, Abulaban Ahmad A
Department of Medicine, King Abdulaziz Medical City, National Guard Health Affairs, Riyadh, Saudi Arabia.
Case Rep Neurol. 2016 Feb 12;8(1):47-52. doi: 10.1159/000443787. eCollection 2016 Jan-Apr.
Spinal cord schistosomiasis is difficult to diagnose in nonendemic areas. We report the clinical profile of 2 young Saudi males who presented with myelopathy. The first patient arrived at our hospital relatively late, i.e. 3 months following the presentation of initial symptoms, and had received both pulse steroid therapy and a plasma exchange. Praziquantel was administered late and the patient did not recover. The second case presented early, i.e. within around 8 weeks of initial symptoms. This patient received praziquantel without any kind of steroid and had a complete recovery. We concluded that prompt recognition and early treatment with praziquantel is crucial for a better outcome. The role of steroids in these cases still needs to be proven.
脊髓血吸虫病在非流行地区难以诊断。我们报告了2名出现脊髓病的沙特年轻男性的临床情况。第一名患者到我院时相对较晚,即在出现初始症状3个月后,已接受了脉冲类固醇治疗和血浆置换。吡喹酮给药较晚,患者未康复。第二例患者就诊较早,即在初始症状出现后约8周内。该患者未使用任何类固醇药物接受了吡喹酮治疗,且完全康复。我们得出结论,及时识别并早期使用吡喹酮治疗对于取得更好的结果至关重要。类固醇在这些病例中的作用仍有待证实。