Hu Dayong, Li Changbin, Sun Liping, Zhou Chunyu, Li Xinhua, Ai Zisheng, Tang Jie, Peng Ai
Department of Nephrology and Rheumatology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, PR China.
Department of Ultrasound in Medicine, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, PR China.
J Vasc Surg. 2016 Oct;64(4):1059-65. doi: 10.1016/j.jvs.2016.03.450. Epub 2016 Jun 11.
With the growing need for reliable and durable upper arm hemodialysis access, we sought to compare the performance of a novel modified nontransposed brachiobasilic arteriovenous fistula (mNT-BBAVF) with that of the more traditional brachiocephalic arteriovenous fistula (BCAVF).
Briefly, to construct an mNT-BBAVF, an incision is made on the ulnar side of the elbow. The brachial artery and basilic vein are then isolated, and a side-to-side anastomosis is performed without transposition of the basilic vein. Next, the proximal basilic vein and the perforating veins within the surgical field are ligated. In this study, we retrospectively reviewed the medical records of all patients who underwent either an mNT-BBAVF or a BCAVF between January 2011 and October 2014 to compare 1-year primary unassisted patency, cumulative patency, and complications. We also examined hemodynamic parameters of vessels in each fistula type.
We identified a total of 84 patients: 45 had a BCAVF, and 39 had an mNT-BBAVF. The two groups were well matched for baseline characteristics. Maturation rates at 1 month were 97% for mNT-BBAVF and 96% for BCAVF. The 1-year primary unassisted patency was significantly higher in the mNT-BBAVF group than that in the BCAVF group (87% vs 67%; hazard ratio, 2.86; 95% confidence interval, 1.11-6.40; P = .03), although cumulative patency did not differ (90% vs 73%; hazard ratio, 2.80; 95% confidence interval, 0.98-6.96 ; P = .06). There were no differences in thrombosis, failure of maturation, bleeding, steal syndrome, arm swelling, aneurysm, and stenosis between the two groups during the 12-month study. Importantly, diameters and blood flow volumes of the proximal cephalic vein, distal cephalic vein, and distal basilic vein in patients who received an mNT-BBAVF increased significantly after 12 months. All three vessels met the Kidney Disease Outcomes Quality Initiative (KDOQI) criteria for fistula maturation and were available for dialysis cannulation, whereas only the proximal cephalic vein in the BCAVF group met the maturation criteria and could be used for cannulation.
mNT-BBAVF appeared to be an effective alternative to BCAVF for upper arm hemodialysis access.
随着对可靠且耐用的上臂血液透析通路需求的不断增加,我们试图比较新型改良非转位肱静脉-头静脉内瘘(mNT - BBAVF)与更传统的头臂动静脉内瘘(BCAVF)的性能。
简要来说,构建mNT - BBAVF时,在肘部尺侧做切口。然后分离肱动脉和头静脉,在不转位头静脉的情况下进行端侧吻合。接下来,结扎手术区域内的近端头静脉和穿支静脉。在本研究中,我们回顾性分析了2011年1月至2014年10月期间接受mNT - BBAVF或BCAVF手术的所有患者的病历,以比较1年的初次非辅助通畅率、累积通畅率和并发症情况。我们还检查了每种内瘘类型血管的血流动力学参数。
我们共纳入84例患者:45例行BCAVF手术,39例行mNT - BBAVF手术。两组患者的基线特征匹配良好。mNT - BBAVF组1个月时的成熟率为97%,BCAVF组为96%。mNT - BBAVF组的1年初次非辅助通畅率显著高于BCAVF组(87%对67%;风险比,2.86;95%置信区间,1.11 - 6.40;P = 0.03),尽管累积通畅率无差异(90%对73%;风险比,2.80;95%置信区间,0.98 - 6.96;P = 0.06)。在为期12个月的研究中,两组在血栓形成、成熟失败、出血、窃血综合征、手臂肿胀、动脉瘤和狭窄方面均无差异。重要的是,接受mNT - BBAVF手术的患者,其近端头静脉、远端头静脉和远端头臂静脉的直径和血流量在12个月后显著增加。这三条血管均符合肾脏病预后质量倡议(KDOQI)的内瘘成熟标准,可用于透析穿刺,而BCAVF组只有近端头静脉符合成熟标准且可用于穿刺。
对于上臂血液透析通路,mNT - BBAVF似乎是BCAVF的一种有效替代方案。