Taniguchi Tohru, Asahata Mai, Nasu Akihito, Shichibu Yukatsu, Konishi Katsuaki, Monde Kenji
Faculty of Advanced Life Science, Frontier Research Center for Post-Genome Science and Technology, Hokkaido University, Sapporo, Japan.
Faculty of Environmental Earth Science, Hokkaido University, Sapporo, Japan.
Chirality. 2016 Jul;28(7):534-9. doi: 10.1002/chir.22610. Epub 2016 Jun 14.
Separation of the diastereomers of glycosyl sulfoxides differing in the sulfur chirality has been difficult. This article presents a fast and scalable method for their diastereoseparation using a chiral stationary phase. The usefulness of this method was demonstrated in a 500-mg scale separation within 20 min, and in the separation of trisaccharyl sulfoxide diastereomers. Chirality 28:534-539, 2016. © 2016 Wiley Periodicals, Inc.
分离硫手性不同的糖基亚砜非对映异构体一直很困难。本文提出了一种使用手性固定相快速且可扩展的非对映体分离方法。该方法的实用性在20分钟内500毫克规模的分离以及三糖基亚砜非对映异构体的分离中得到了证明。《手性》2016年第28卷，第534 - 539页。© 2016威利期刊公司。
