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一名5个月大儿童在使用成人用福来灌肠剂后出现严重高磷血症、低钙血症、酸中毒和休克。

Severe hyperphosphatemia, hypocalcemia, acidosis, and shock in a 5-month-old child following the administration of an adult Fleet enema.

作者信息

Wason S, Tiller T, Cunha C

机构信息

Emergency Department, Children's Hospital Medical Center, Cincinnati, Ohio.

出版信息

Ann Emerg Med. 1989 Jun;18(6):696-700. doi: 10.1016/s0196-0644(89)80533-5.

DOI:10.1016/s0196-0644(89)80533-5
PMID:2729698
Abstract

We report the case of a 5-month-old girl who was given an adult Fleet enema by her mother because of her concern that the baby was constipated. Within minutes the child became extremely ill. She developed shock, hyperphosphatemia, hypocalcemia, and acidosis. This case is presented to demonstrate that life-threatening events may result after the injudicious use of enemas in children.

摘要

我们报告一例5个月大女童的病例,其母亲因担心孩子便秘,给她使用了成人剂量的灌肠剂。几分钟内,孩子病情急剧恶化。她出现了休克、高磷血症、低钙血症和酸中毒。此病例旨在表明,儿童不当使用灌肠剂可能导致危及生命的后果。

相似文献

1
Severe hyperphosphatemia, hypocalcemia, acidosis, and shock in a 5-month-old child following the administration of an adult Fleet enema.一名5个月大儿童在使用成人用福来灌肠剂后出现严重高磷血症、低钙血症、酸中毒和休克。
Ann Emerg Med. 1989 Jun;18(6):696-700. doi: 10.1016/s0196-0644(89)80533-5.
2
Hypocalcemia and hyperphosphatemia after phosphate enema use in a child.
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3
Severe hyperphosphatemia and hypocalcemia following the rectal administration of a phosphate-containing Fleet pediatric enema.
Pediatr Emerg Care. 2004 Jul;20(7):453-6. doi: 10.1097/01.pec.0000132217.65600.52.
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Fatal hypocalcemic, hyperphosphatemic, metabolic acidosis following sequential sodium phosphate-based enema administration.连续给予磷酸钠灌肠剂后出现致命性低钙血症、高磷血症和代谢性酸中毒。
Gastrointest Endosc. 1997 Sep;46(3):266-8. doi: 10.1016/s0016-5107(97)70099-3.
5
Hypocalcemia, hyperphosphatemia, and dehydration following a single hypertonic phosphate enema.单次高渗磷酸盐灌肠后出现低钙血症、高磷血症和脱水。
J Pediatr. 1977 Mar;90(3):484-5. doi: 10.1016/s0022-3476(77)80723-3.
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Hypocalcemic coma following two pediatric phosphate enemas.
Pediatrics. 1977 Sep;60(3):305-7.
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Enema-induced hyperphosphatemia.灌肠诱导的高磷血症。
Am J Med. 1985 Nov;79(5):645-6. doi: 10.1016/0002-9343(85)90064-6.
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Severe hyperphosphatemia and hypocalcemia: a dilemma in patient management.
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[Tetany secondary to phosphate enema toxicity, case report].
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Extreme hyperphosphatemia and hypocalcemic coma associated with phosphate enema.与磷酸盐灌肠剂相关的极重度高磷血症和低钙血症昏迷。
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引用本文的文献

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Effects of a 250-mL enema containing sodium phosphate on electrolyte concentrations in healthy volunteers: An open-label, randomized, controlled, two-period, crossover clinical trial.含磷酸钠的250毫升灌肠剂对健康志愿者电解质浓度的影响:一项开放标签、随机、对照、两期交叉临床试验。
Curr Ther Res Clin Exp. 2006 Sep;67(5):334-49. doi: 10.1016/j.curtheres.2006.10.004.
2
Severe hyperphosphatemia after administration of sodium-phosphate containing laxatives in children: case series and systematic review of literature.儿童服用含磷酸钠泻药后出现严重高磷血症:病例系列及文献系统综述
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Respiratory failure requiring extracorporeal membrane oxygenation after sodium phosphate enema intoxication.
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A 4-year-old girl with manifestations of multiple chemical sensitivities.一名患有多种化学物质过敏症的4岁女孩。
Environ Health Perspect. 2000 Dec;108(12):1219-23. doi: 10.1289/ehp.001081219.