Blackie S P, Fairbarn M S, McElvaney G N, Morrison N J, Wilcox P G, Pardy R L
University of British Columbia, St. Paul's Hospital, Vancouver, Canada.
Am Rev Respir Dis. 1989 Jun;139(6):1424-9. doi: 10.1164/ajrccm/139.6.1424.
One hundred twenty-eight healthy volunteers (81 women, 47 men) older than 55 yr of age were studied with an incremental progressive cycle ergometer test to a symptom-limited, maximal tolerable work load. Mean (+/- SD) age was 66 +/- 6 yr in women and 66 +/- 5 years in men. Subjects with a history of ischemic heart disease, diabetes, pulmonary disease, or neuromuscular disease were excluded. Smokers were included, but all subjects had normal FEV1 and FVC. The objective of the study was to compare measured values of VO2max and Wmax in this older population with previously published predicted values based on subjects of all ages. We found that Wmax observed exceeded Wmax predicted by 9.5 +/- 22% (mean +/- SD) and that VO2max observed exceeded VO2max predicted by 17.5 +/- 22%. Because of this systematic underestimate of VO2max and Wmax by the previous prediction equations, we constructed new prediction equations for use in subjects older than 55 yr of age using height, weight, age, and sex as variables. We conclude that these new prediction equations more accurately predict Wmax and VO2max in subjects older than 55 yr of age because they are based solely on subjects in this age group.
对128名年龄超过55岁的健康志愿者（81名女性，47名男性）进行了递增式渐进性蹬车测力计测试，直至达到症状限制的最大耐受工作量。女性的平均（±标准差）年龄为66±6岁，男性为66±5岁。有缺血性心脏病、糖尿病、肺部疾病或神经肌肉疾病史的受试者被排除。吸烟者被纳入研究，但所有受试者的第一秒用力呼气容积（FEV1）和用力肺活量（FVC）均正常。本研究的目的是将该老年人群的最大摄氧量（VO2max）和最大工作量（Wmax）测量值与之前基于所有年龄段受试者发表的预测值进行比较。我们发现，观察到的Wmax超过预测的Wmax 9.5±22%（平均±标准差），观察到的VO2max超过预测的VO2max 17.5±22%。由于之前的预测方程对VO2max和Wmax存在系统性低估，我们以身高、体重、年龄和性别为变量，构建了适用于55岁以上受试者的新预测方程。我们得出结论，这些新的预测方程能更准确地预测55岁以上受试者的Wmax和VO2max，因为它们仅基于该年龄组的受试者。
