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跟骨溶骨性病变导致术后出血的罕见原因

A Rare Cause of Postoperative Bleeding from A Lytic Lesion of Calcaneum.

作者信息

Kamath Surendra U, Kamath Shaila S

机构信息

Department of Orthopaedics, Kasturba Medical College Hospital, Attavar, Manipal University, Manipal. India.

Department of Anaesthesiology, Kasturba Medical College Hospital, Attavar, Manipal University, Manipal. India.

出版信息

J Orthop Case Rep. 2015 Jan-Mar;5(1):31-3. doi: 10.13107/jocr.2250-0685.249.

Abstract

INTRODUCTION

Post-operative excessive bleeding can be due to various causes, which may platelet deficiency, both quantitative and qualitative, vascular disorder, clotting factor defects and excessive fibrinolysis. Rarely can be due to some undiagnosed malignant tumours. Angiosarcoma of bone is an exceedingly rare primary bone malignancy. We report an interesting and rare case of an intraosseous angiosarcoma that presented as an excessive postoperative bleeding with diagnostic dilemma.

CASE REPORT

A twenty eight year old gentleman admitted to our hospital with history of continuous bleeding from surgical site over left heel since three months. About six months ago he was evaluated elsewhere for a painful progressive lesion in the left calcaneum. Following which he underwent curettage of lesion with bone grafting. One month after this he was re-operated for recurrence with curettage with bone cementing. Curetted material on both occasions was reported as aneurysmal bone cyst. One month following the second surgery, surgical scar over the outer aspect of left heel opened out and started to bleed continuously. X rays and MRI done before surgical treatment were suggestive of aneurysmal bone cyst Investigations for clotting and bleeding disorders were normal. The granulation tissue from the floor of the cavity was curetted and sent for histopathology, which was reported as angiosarcoma.

CONCLUSION

Intraosseous angiosarcoma is a rare primary bone tumour. The diagnosis is often delayed because of the non-specific clinical presentation and radiological features. Clinicopathological correlation is very important to differentiate aneurysmal bone cyst from the aggressive type of vascular malignancies. The clinical course of disease is aggressive, as demonstrated by this current case. The initial biopsies done twice at curettage were not diagnostic and suggested the presence of a benign aneurysmal bone cyst. Due to the excessive postoperative bleeding, repeat biopsy performed which diagnosed angiosarcoma.

摘要

引言

术后出血过多可能由多种原因引起,包括血小板数量和质量不足、血管疾病、凝血因子缺陷以及纤维蛋白溶解过度。极少数情况下可能是由于某些未被诊断出的恶性肿瘤。骨血管肉瘤是一种极其罕见的原发性骨恶性肿瘤。我们报告了一例有趣且罕见的骨内血管肉瘤病例,该病例表现为术后出血过多且诊断困难。

病例报告

一名28岁男性因左足跟手术部位持续出血3个月入住我院。大约6个月前,他因左跟骨疼痛性进行性病变在其他地方接受评估。之后他接受了病灶刮除术并植骨。术后1个月,因复发再次进行刮除并骨水泥填充手术。两次刮除的组织均报告为骨囊肿。第二次手术后1个月,左足跟外侧手术切口裂开并开始持续出血。手术治疗前的X线和MRI检查提示为骨囊肿。凝血和出血障碍检查均正常。刮除了腔底部的肉芽组织并送去做组织病理学检查,结果报告为血管肉瘤。

结论

骨内血管肉瘤是一种罕见的原发性骨肿瘤。由于临床表现和影像学特征不具有特异性,诊断往往会延迟。临床病理相关性对于区分骨囊肿和侵袭性血管恶性肿瘤非常重要。正如本病例所示,该病的临床病程具有侵袭性。最初两次刮除活检均未确诊,提示为良性骨囊肿。由于术后出血过多,进行了重复活检,最终诊断为血管肉瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8768/4719348/dcef82c6aa51/JOCR-5-31-g001.jpg

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