Bjørnnes Ann Kristin, Parry Monica, Lie Irene, Fagerland Morten Wang, Watt-Watson Judy, Rustøen Tone, Stubhaug Audun, Leegaard Marit
Division of Emergencies and Critical Care, Department of Research and Development, Oslo University Hospital, Oslo, Norway.
Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
J Clin Nurs. 2016 Oct;25(19-20):3058-68. doi: 10.1111/jocn.13329. Epub 2016 Jun 15.
To compare the prevalence and severity of pain in men and women during the first year following cardiac surgery and to examine the predictors of persistent postoperative pain 12 months post surgery.
Persistent pain has been documented after cardiac surgery, with limited evidence for differences between men and women.
Prospective cohort study of patients in a randomised controlled trial (N = 416, 23% women) following cardiac surgery.
Secondary data analysis of data collected prior to surgery, across postoperative days 1-4, at two weeks, and at one, three, six and 12 months post surgery. The main outcome was worst pain intensity (Brief Pain Inventory-Short Form).
Twenty-nine percent (97/339) of patients reported persistent postoperative pain at rest at 12 months that was worse in intensity and interference for women than for men. For both sexes, a more severe co-morbidity profile, lower education and postoperative pain at rest at one month post surgery were associated with an increased probability for persistent postoperative pain at 12 months. Women with more concerns about communicating pain and a lower intake of analgesics in the hospital had an increased probability of pain at 12 months.
Sex differences in pain are present up to one year following cardiac surgery. Strategies for sex-targeted pain education and management pre- and post-surgery may lead to better pain outcomes.
These results suggest that informing patients (particularly women) about the benefits of analgesic use following cardiac surgery may result in less pain over the first year post discharge.
比较心脏手术后第一年男性和女性疼痛的患病率和严重程度,并研究术后12个月持续疼痛的预测因素。
心脏手术后已证实存在持续性疼痛,关于男性和女性之间差异的证据有限。
对心脏手术后随机对照试验中的患者进行前瞻性队列研究(N = 416,23%为女性)。
对术前、术后第1 - 4天、两周、术后1个月、3个月、6个月和12个月收集的数据进行二次数据分析。主要结局是最严重疼痛强度(简明疼痛量表简表)。
29%(97/339)的患者在术后12个月报告静息时存在持续性疼痛,女性的疼痛强度和干扰程度比男性更严重。对于男女两性而言,更严重的共病情况、较低的教育程度以及术后1个月静息时的疼痛与术后12个月持续性疼痛的可能性增加有关。对疼痛沟通更为担忧且住院期间镇痛药摄入量较低的女性,术后12个月疼痛的可能性增加。
心脏手术后长达一年存在疼痛的性别差异。术前和术后针对性别的疼痛教育和管理策略可能会带来更好的疼痛结局。
这些结果表明,告知患者(尤其是女性)心脏手术后使用镇痛药的益处可能会使出院后第一年的疼痛减轻。