依托度酸和布洛芬在性别方面对下颌第三磨牙阻生术后疼痛、肿胀和牙关紧闭的疗效：一项随机前瞻性临床分侧研究。
The efficacy of etodolac and ibuprofen, regarding gender, on pain, edema and trismus after impacted lower third molar surgery: A randomized prospective clinical split-mouth study.
机构信息
José Bonifácio street number 1193 16015-050, Araçatuba, São Paulo, Brazil
出版信息
Med Oral Patol Oral Cir Bucal. 2021 Mar 1;26(2):e136-e140. doi: 10.4317/medoral.24082.
BACKGROUND
This study aimed to conduct a randomized prospective study about the efficacy of etodolac and ibuprofen on trismus, pain and edema regarding gender of patients submitted to impacted lower third molar teeth extraction.
MATERIAL AND METHODS
Thirty patients aging between 16 and 35 year-old were submitted to the exodontia of impacted lower third molars. During the postoperative period, patients received nine ibuprofen (600 mg) or etodolac (300 mg) pills via oral administration immediately after surgery and repeated doses every eight hours during three days. Patients were evaluated regarding pain, trismus and edema.
RESULTS
Sixteen men and fourteen women participated of the study. No statistical difference was established regarding gender according to the evaluated parameters. However, etodolac use showed better results regarding pain, trismus and edema.
CONCLUSIONS
Pain, edema and trismus after impacted third molars extraction were not influenced by gender.
背景
本研究旨在进行一项随机前瞻性研究，评估依托度酸和布洛芬对接受下颌第三磨牙阻生牙拔除术的患者的牙关紧闭、疼痛和肿胀的疗效是否与患者的性别有关。
材料与方法
30 名年龄在 16 至 35 岁之间的患者接受了下颌第三磨牙阻生牙的拔除术。术后期间，患者接受了 9 片布洛芬（600mg）或依托度酸（300mg）的口服给药，术后立即服用，并在三天内每八小时重复服用一次。患者接受了疼痛、牙关紧闭和肿胀的评估。
结果
16 名男性和 14 名女性参与了这项研究。根据评估的参数，性别之间没有统计学差异。然而，依托度酸的使用在疼痛、牙关紧闭和肿胀方面显示出更好的效果。
结论
下颌第三磨牙阻生牙拔除术后的疼痛、肿胀和牙关紧闭不受性别影响。
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