Bookstein F L, DePaola P F
J Dent Res. 1977 Oct;56 Spec No:C40-5. doi: 10.1177/002203457705600315011.
A model relating caries to surface enamel fluoride and plaque has been derived by exploratory data analyses. Since the model was obtained a posteriori, it is best viewed in qualitative terms as a hypothesis for future testing. The model prompts a re-evaluation of expectations relative to the effects of surface enamel apatitic fluoride, and a consideration that the effectiveness of a given measure of fluoride may vary as a function of inherent challenge. Thus, further studies are needed, aimed at quantifying the parameters of resistance and challenge, and characterizing the relationship between them.
通过探索性数据分析得出了一个将龋齿与表层釉质氟化物及牙菌斑相关联的模型。由于该模型是事后获得的，从定性角度看，它最好被视为一个有待未来检验的假设。该模型促使人们重新评估对表层釉质磷灰石氟化物作用的预期，并考虑到给定氟化物措施的有效性可能会因固有挑战而有所不同。因此，需要进一步开展研究，旨在量化抵抗力和挑战的参数，并描述它们之间的关系。
