颅内脑膜瘤手术切除后肿瘤细胞在大腿软组织中的医源性播散。
Iatrogenic Seeding of Tumor Cells in Thigh Soft Tissue Upon Surgical Removal of Intracranial Meningioma.
作者信息
Maddah Ghodratollah, Shabahang Hossein, Zehi Vahid, Sharifi Sistani Nouriyeh, Mashhadi Nejad Hossein
机构信息
Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Department of Pathology, Ghaem Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
出版信息
Basic Clin Neurosci. 2016 Apr;7(2):159-64. doi: 10.15412/J.BCN.03070209.
INTRODUCTION
Meningioma is a benign and slowly-growing tumor that is responsible for 20% of brain neoplasms. It can be accompanied by some genetic disorders such as neurofibromatosis type 2 and is more common among women. As a space occupying lesion, it produces a wide range of signs and symptoms by compressing the adjacent and underlying tissues in the brain. Trauma and viruses are possible etiologies for meningioma. The ideal treatment of benign meningioma is surgical resection.
CASE PRESENTATION
In this case report, we present a middle-aged man with a seeding metastasis of the cranial meningioma (after its removal) in the left thigh. During the removal operation, fascia lata had been used to repair the dura mater and the skin defect was repaired primarily.
CONCLUSION
We believe that the occurrence of meningioma at the site of incision in the thigh is related to using the same surgical instruments for the removal of the brain tumor.
引言
脑膜瘤是一种良性且生长缓慢的肿瘤，占脑肿瘤的20%。它可能伴有一些遗传性疾病，如2型神经纤维瘤病，在女性中更为常见。作为一种占位性病变，它通过压迫大脑中相邻和下方的组织产生广泛的体征和症状。创伤和病毒可能是脑膜瘤的病因。良性脑膜瘤的理想治疗方法是手术切除。
病例报告
在本病例报告中，我们介绍了一名中年男性，其左大腿出现了颅脑膜瘤（切除后）的播散性转移。在切除手术过程中，使用阔筋膜修复硬脑膜，皮肤缺损进行了一期修复。
结论
我们认为大腿切口部位出现脑膜瘤与使用相同的手术器械切除脑肿瘤有关。
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