Rouse Barry T, Mueller Scott N
Department of Pathobiology, College of Veterinary Medicine, University of Tennessee, Knoxville, TN, USA.
Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Victoria, Australia.
F1000Res. 2016 May 27;5. doi: 10.12688/f1000research.8391.1. eCollection 2016.
The field of viral immunology seeks to understand mechanisms of virus-host interaction with a view of applying this knowledge to the design of effective vaccines and immunomodulators that control viral infections. This brief review discusses several areas of the field that hold substantial promise for translation, but where further work is critically required to find solutions. We emphasize that our fundamental understanding of virus-host relationships is moving in leaps and bounds, but we lag behind in applying this knowledge to the successful control of many viral infections.
病毒免疫学领域旨在了解病毒与宿主相互作用的机制，以期将这些知识应用于设计控制病毒感染的有效疫苗和免疫调节剂。本简要综述讨论了该领域中几个具有重大转化前景但急需进一步研究以找到解决方案的领域。我们强调，我们对病毒与宿主关系的基本理解正在飞速发展，但在将这些知识成功应用于控制多种病毒感染方面，我们仍落后于人。
