Section of Immunobiology, Division of Inflammation and Immunology, Department of Medicine, Faculty of Medicine, Imperial College London, Norfolk Place, London W2 1PG, UK.
Cell Metab. 2016 Jun 14;23(6):967-968. doi: 10.1016/j.cmet.2016.05.018.
The development and function of cytotoxic CD8 T cells (CTLs), which provide immunity to viral infections, are regulated by changes in mitochondrial respiration. Champagne et al. (2016) describe a new mechanism through which mitochondrial metabolism controls production of ATP required for the secretion of critical anti-viral molecules by CTLs.
细胞毒性 CD8 T 细胞（CTLs）的发育和功能受线粒体呼吸变化的调节，CTLs 为病毒感染提供免疫力。Champagne 等人（2016 年）描述了一种新的机制，通过该机制，线粒体代谢控制 CTLs 分泌关键抗病毒分子所需的 ATP 的产生。
