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从探索三氯生和三氯卡班对人类微生物组的影响中吸取的教训。

Lessons Learned from Probing for Impacts of Triclosan and Triclocarban on Human Microbiomes.

机构信息

Biodesign Center for Environmental Security, Biodesign Institute, School of Sustainable Engineering and the Built Environment, and Global Security Initiative, Arizona State University, Tempe, Arizona, USA, and Environmental Chemistry Department, Swiss Federal Institute of Aquatic Science and Technology (EAWAG), Dübendorf, Switzerland.

出版信息

mSphere. 2016 May 18;1(3). doi: 10.1128/mSphere.00089-16. eCollection 2016 May-Jun.

Abstract

Despite increasing interest in the effects of triclosan and triclocarban on human biology, current knowledge is still limited on the impact of these additives to antimicrobial personal care products on the human microbiome. A carefully designed recent study published in mSphere by Poole and colleagues [A. C. Poole et al., mSphere 1(3):e00056-15, 2016, http://dx.doi.org/10.1128/mSphere.00056-15] highlights both the power of novel methodologies for microbiome elucidation and the longstanding challenge of employing small-cohort studies to inform risk assessment for chemicals of ubiquitous use in modern society.

摘要

尽管人们对三氯生和三氯卡班对人类生物学的影响越来越感兴趣,但目前关于这些抗菌个人护理产品添加剂对人类微生物组的影响的知识仍然有限。最近在 mSphere 上发表的一项由 Poole 及其同事精心设计的研究[A. C. Poole 等人,mSphere 1(3):e00056-15, 2016, http://dx.doi.org/10.1128/mSphere.00056-15]强调了新的微生物组阐明方法的强大功能,以及长期以来利用小队列研究为现代社会中广泛使用的化学物质的风险评估提供信息所面临的挑战。

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