Furlan Julio C, Craven Beverly Catharine, Fehlings Michael G
*Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada; ‡Division of Physical Medicine and Rehabilitation, Department of Medicine, University of Toronto, Toronto, Ontario, Canada; §Lyndhurst Centre, Toronto Rehabilitation Institute, University Health Network, Toronto, Ontario, Canada; ¶Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, Ontario, Canada; ‖Krembil Neuroscience Centre, Spinal Program, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada.
Neurosurgery. 2016 Sep;79(3):418-25. doi: 10.1227/NEU.0000000000001314.
Aging of the population has modified the epidemiology of traumatic spinal cord injury (SCI) as evidenced by the establishment of a bimodal distribution of injuries with increased frequency of fall-related injuries among the elderly.
To assess the economic impact of older age (65 years of age and older), using a cost-utility analysis, in the context of acute surgical management and rehabilitation of traumatic cervical SCI, given the paucity of economic studies involving elderly individuals with SCI.
The cost-utility analysis was performed from the perspective of a public health care insurer. A time horizon of 6 months from SCI onset was used. Costs were estimated in 2014 US dollars. Utilities were generated from the Surgical Timing in Acute Spinal Cord Injury study.
The baseline analysis indicated that surgical and rehabilitative management of acute cervical SCI in the elderly (n = 17) is costlier, but similarly effective, than that in younger adults (n = 47). When considering acute spinal surgical management and rehabilitation of younger adults with SCI as the baseline, the incremental cost-effectiveness ratio analysis revealed an additional cost of $5 655 557 per quality-adjusted life-year gained when managing elderly patients with traumatic cervical SCI. The probabilistic analysis confirmed that spinal surgery in the elderly is costlier, but similarly effective, in younger adults after SCI, even though there is no definitive dominance.
This economic analysis indicates that surgical management and rehabilitation of acute traumatic cervical SCI in the elderly are costlier but similarly effective compared with younger adults with similar impairment.
AIS, ASIA (American Spinal Injury Association) Impairment Scale.
人口老龄化改变了创伤性脊髓损伤(SCI)的流行病学,这一点从损伤的双峰分布的确立以及老年人中与跌倒相关损伤频率的增加得到了证明。
鉴于涉及老年SCI患者的经济研究较少,在创伤性颈髓SCI的急性手术治疗和康复背景下,采用成本效用分析评估老年(65岁及以上)的经济影响。
成本效用分析是从公共医疗保险公司的角度进行的。使用了从SCI发病起6个月的时间范围。成本以2014年美元估算。效用值来自急性脊髓损伤手术时机研究。
基线分析表明,老年患者(n = 17)急性颈髓SCI的手术和康复治疗比年轻成人(n = 47)更昂贵,但效果相似。以年轻成人SCI患者的急性脊柱手术治疗和康复作为基线,增量成本效果比分析显示,治疗老年创伤性颈髓SCI患者时,每获得一个质量调整生命年需额外花费5655557美元。概率分析证实,老年患者的脊柱手术在SCI后比年轻成人更昂贵,但效果相似,尽管没有绝对优势。
这项经济分析表明,与有类似损伤的年轻成人相比老年急性创伤性颈髓SCI的手术治疗和康复成本更高,但效果相似。
AIS,美国脊髓损伤协会(ASIA)损伤量表