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双侧面瘫:13年的经验总结

Bilateral Facial Paralysis: A 13-Year Experience.

作者信息

Gaudin Robert A, Jowett Nathan, Banks Caroline A, Knox Christopher J, Hadlock Tessa A

机构信息

Boston, Mass.

From the Department of Otolaryngology, Massachusetts Eye and Ear Infirmary and Harvard Medical School.

出版信息

Plast Reconstr Surg. 2016 Oct;138(4):879-887. doi: 10.1097/PRS.0000000000002599.

Abstract

BACKGROUND

Bilateral facial palsy is a rare clinical entity caused by myriad disparate conditions requiring different treatment paradigms. Lyme disease, Guillain-Barré syndrome, and leukemia are several examples. In this article, the authors describe the cause, the initial diagnostic approach, and the management of long-term sequelae of bilateral paralysis that has evolved in the authors' center over the past 13 years.

METHODS

A chart review was performed to identify all patients diagnosed with bilateral paralysis at the authors' center between January of 2002 and January of 2015. Demographics, signs and symptoms, diagnosis, initial medical treatment, interventions for facial reanimation, and outcomes were reviewed.

RESULTS

Of the 2471 patients seen at the authors' center, 68 patients (3 percent) with bilateral facial paralysis were identified. Ten patients (15 percent) presented with bilateral facial paralysis caused by Lyme disease, nine (13 percent) with Möbius syndrome, nine (13 percent) with neurofibromatosis type 2, five (7 percent) with bilateral facial palsy caused by brain tumor, four (6 percent) with Melkersson-Rosenthal syndrome, three (4 percent) with bilateral temporal bone fractures, two (3 percent) with Guillain-Barré syndrome, one (2 percent) with central nervous system lymphoma, one (2 percent) with human immunodeficiency virus infection, and 24 (35 percent) with presumed Bell palsy. Treatment included pharmacologic therapy, physical therapy, chemodenervation, and surgical interventions.

CONCLUSIONS

Bilateral facial palsy is a rare medical condition, and treatment often requires a multidisciplinary approach. The authors outline diagnostic and therapeutic algorithms of a tertiary care center to provide clinicians with a systematic approach to managing these complicated patients.

摘要

背景

双侧面瘫是一种罕见的临床病症,由多种不同病因引起,需要不同的治疗模式。莱姆病、格林-巴利综合征和白血病就是其中几个例子。在本文中,作者描述了在过去13年里在作者所在中心演变的双侧面瘫的病因、初始诊断方法以及长期后遗症的管理。

方法

进行了一项病历回顾,以确定2002年1月至2015年1月期间在作者所在中心被诊断为双侧面瘫的所有患者。回顾了人口统计学资料、体征和症状、诊断、初始药物治疗、面部重建干预措施以及治疗结果。

结果

在作者所在中心就诊的2471例患者中,有68例(3%)被确定为双侧面瘫。10例(15%)患者因莱姆病导致双侧面瘫,9例(13%)患有莫比乌斯综合征,9例(13%)患有2型神经纤维瘤病,5例(7%)因脑肿瘤导致双侧面瘫,4例(6%)患有梅尔克森-罗森塔尔综合征,3例(4%)双侧颞骨骨折,2例(3%)患有格林-巴利综合征,1例(2%)患有中枢神经系统淋巴瘤,1例(2%)感染人类免疫缺陷病毒,24例(35%)为疑似贝尔面瘫。治疗包括药物治疗、物理治疗、化学去神经支配和手术干预。

结论

双侧面瘫是一种罕见的病症,治疗通常需要多学科方法。作者概述了三级医疗中心的诊断和治疗算法,为临床医生提供一种系统的方法来管理这些复杂的患者。

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